Anti Phospholipid Antibody, IgG

The Anti Phospholipid Antibody, IgG test measures specific IgG antibodies that are associated with antiphospholipid syndrome (APS). Identifying these antibodies is crucial for diagnosing APS, especially in cases where symptoms are unusual or accompanied by other autoimmune diseases.

The Anti Phospholipid Antibody, IgG test helps identify the cause of unexplained blood clots, low platelet levels, repeated miscarriages, preterm births, and high blood pressure during pregnancy (preeclampsia). The presence of IgG antibodies in the blood is considered a more reliable and significant sign of risk for APS and suggests a higher chance of blood clots and long-term health problems.

The Anti Phospholipid Antibody, IgG test is recommended for individuals who have had unexplained blood clots, multiple miscarriages, or other symptoms related to APS, like stroke or repeated pregnancy losses. It can also track disease activity and see how well treatment works for those already diagnosed with APS or other autoimmune conditions like lupus (SLE). The test may also be suggested for people with a history of blood clots or pregnancy problems to check the risk of future clots and help plan the right treatment, such as blood thinners. Additionally, the test can help diagnose APS in its later stages, as IgG antibodies appear at this point, showing the body’s long-term immune response.

For this test, a duly filled coagulation requisition form (Annexure - CR/05) is mandatory for sample collection. This form can be provided by the laboratory personnel (phlebotomist) before sample withdrawal. It is also recommended to discontinue heparin for 1 day and oral anticoagulants for 7 days before sample collection, or as the doctor advises.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results. Always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.