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Anti Smooth Muscle Antibody, IFA near me in Mumbai
Also known as Smooth Muscle Antibody, Actin Antibody
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Blood
This test is for
Male, Female
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Understanding Anti Smooth Muscle Antibody, IFA in Mumbai
What is Anti Smooth Muscle Antibody, IFA in Mumbai?
The Anti Smooth Muscle Antibody, IFA test is a blood test used to detect the presence of autoantibodies made against smooth muscle cells, often in the liver. This test helps in the diagnosis of autoimmune liver diseases, particularly autoimmune hepatitis (AIH).
The Anti Smooth Muscle Antibody, IFA test detects Immunoglobulin G (IgG) antibodies targeting actin filaments in smooth muscle cells using the sensitive, gold standard indirect immunofluorescence Assay (IFA) method. However, this test is meant for screening purposes only and is not intended as a standalone test. It should be used in conjunction with clinical evaluation and other laboratory tests, including liver function test (LFT), liver biopsies, etc, to make a definitive diagnosis.
An overnight fasting (8 to 12 hours) is preferred before the Anti Smooth Muscle Antibody, IFA test. However, drinking water is acceptable. Also, it is important to refrain from alcohol consumption the day before the test. Inform your doctor about all the medicines and supplements that you may be taking, as some of them may affect the test results and may need to be adjusted or temporarily discontinued before the test.
What does Anti Smooth Muscle Antibody, IFA measure?
The Anti Smooth Muscle Antibody, IFA test measures the levels of anti-smooth muscle antibodies (ASMA) in the blood. These antibodies primarily target the smooth muscle cells within the body, particularly those found in organs like the liver. The presence of these antibodies in the blood indicates an autoimmune activity, particularly in conditions like autoimmune hepatitis (AIH) where the immune system of the body mistakenly attacks the liver cells. Additionally, the Anti Smooth Muscle Antibody, IFA test may be used to detect other autoimmune liver conditions such as primary biliary liver cirrhosis (PBC) and to distinguish between various liver disorders with similar symptoms. This screening test helps in the early detection and timely initiation of treatment against autoimmune hepatitis to prevent further damage to the liver.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Anti Smooth Muscle Antibody, IFA in Mumbai
Frequently Asked Questions about Anti Smooth Muscle Antibody, IFA in Mumbai
Q. What is the purpose of the Anti Smooth Muscle Antibody, IFA test?
The Anti Smooth Muscle Antibody, IFA test is primarily used to help diagnose autoimmune hepatitis, a condition where the immune system mistakenly attacks the liver cells. It can also help evaluate other autoimmune conditions affecting smooth muscles.
Q. When should one get tested for the Anti Smooth Muscle Antibody, IFA test?
One should consider getting tested for the Anti Smooth Muscle Antibody, IFA test if experiencing symptoms suggestive of autoimmune hepatitis like fatigue, jaundice, changes in appetite, abdominal pain, joint pain, etc., or if there are unexplained abnormalities in liver function tests (LFT). Additionally, if there is a family history of autoimmune diseases, or if diagnosed with other autoimmune conditions.
Q. How is the Anti Smooth Muscle Antibody, IFA test performed?
A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
Q. Is there any risk associated with the ASMA test?
No, the ASMA test is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection but chances of serious complications are extremely rare.
Q. What does a positive ASMA result mean?
A positive ASMA result indicates the presence of antibodies against smooth muscle. This is commonly associated with autoimmune hepatitis but can be linked to other autoimmune disorders.
Q. How are ASMA levels used in the management of autoimmune hepatitis?
ASMA levels are used to diagnose autoimmune hepatitis, evaluate the severity of the disease, and monitor the response to treatment. Regular testing can help adjust treatment plans if needed.
Q. Can the ASMA test diagnose other autoimmune disorders besides autoimmune hepatitis?
Despite detecting autoimmune hepatitis, the ASMA test can assist a doctor in determining whether an individual has a liver condition such as primary biliary cirrhosis, or primary sclerosing cholangitis. However, it can also indicate chronic hepatitis C infection, infectious mononucleosis, breast or ovarian cancer, or melanoma.
Q. Can I schedule the Anti Smooth Muscle Antibody, IFA test online in Mumbai near me?
Yes. In Mumbai, you can schedule the Anti Smooth Muscle Antibody, IFA test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Q. Is home sample collection facility available for the Anti Smooth Muscle Antibody, IFA test in Mumbai with Tata 1mg Labs?
Yes, home sample collection for the Anti Smooth Muscle Antibody, IFA test is readily available in Mumbai. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
Q. How can I schedule the Anti Smooth Muscle Antibody, IFA test with Tata 1mg Labs in Mumbai?
If you want to schedule the Anti Smooth Muscle Antibody, IFA test with Tata 1mg Labs in Mumbai, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Q. What is the price of the Anti Smooth Muscle Antibody, IFA test at Tata 1mg Labs in Mumbai?
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Mumbai. The Anti Smooth Muscle Antibody, IFA test is available at an affordable price of Rs. 1909.
Q. How can I get my Anti Smooth Muscle Antibody, IFA test report from Tata 1mg?
The e-report of your Anti Smooth Muscle Antibody, IFA test can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price.
Q. How long does Tata 1mg Labs take to give the reports of the Anti Smooth Muscle Antibody, IFA test in Mumbai?
We at Tata 1mg Labs recognize the value of prompt results. We strive to deliver test results with quick turnaround times so you can receive the information promptly. The reports of the Anti Smooth Muscle Antibody, IFA test in Mumbai are often provided in 216 hours.
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References
- Autoimmune Hepatitis [Internet]. USA: NIDDK; Apr.2023 [Accessed 27 Mar. 2024]. Available from: https://www.niddk.nih.gov/health-information/liver-disease/autoimmune-hepatitis
- Autoimmune Hepatitis [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 27 Mar. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=P00657
- Terziroli Beretta-Piccoli B, Mieli-Vergani G, Vergani D. Autoimmune Hepatitis: Serum Autoantibodies in Clinical Practice. Clin Rev Allergy Immunol. 2022 Oct;63(2):124-137. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464171/
- Sebode M, Weiler-Normann C, Liwinski T, Schramm C. Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance. Front Immunol. 2018 Mar 27;9:609. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880919/
- Mercado LA, Gil-Lopez F, Chirila RM, Harnois DM. Autoimmune Hepatitis: A Diagnostic and Therapeutic Overview. Diagnostics (Basel). 2024 Feb 9;14(4):382. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10887775/
- Zamanou A, Tsirogianni A, Terzoglou C, Balafas A, Economidou I, Lymberi P. Anti-smooth muscle antibodies (ASMAs) and anti-cytoskeleton antibodies (ACTAs) in liver diseases: a comparison of classical indirect immunofluorescence with ELISA. J Clin Lab Anal. 2002;16(4):194-201. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807762/
- Zhang WC, Zhao FR, Chen J, Chen WX. Meta-analysis: diagnostic accuracy of antinuclear antibodies, smooth muscle antibodies and antibodies to a soluble liver antigen/liver pancreas in autoimmune hepatitis. PLoS One. 2014 Mar 20;9(3):e92267. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961308/
- Muratori P, Muratori L, Agostinelli D, Pappas G, Veronesi L, Granito A, Cassani F, Terlizzi P, Lenzi M, Bianchi FB. Smooth muscle antibodies and type 1 autoimmune hepatitis. Autoimmunity. 2002 Dec;35(8):497-500. [Accessed 27 Mar. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/12765475/
- DermNet NZ. Indirect immunofluorescence [Internet]. [Accessed 27 Mar. 2024]. Available from: https://dermnetnz.org/topics/indirect-immunofluorescence
- Terziroli Beretta-Piccoli B, Mieli-Vergani G, Vergani D. Autoimmune Hepatitis: Serum Autoantibodies in Clinical Practice. Clin Rev Allergy Immunol. 2022 Oct;63(2):124-137. [Accessed 27 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464171/
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