Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
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References
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Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Covid Antibody IgG (Quantitative)

Also known as COVID-19 IgG Serology, Sars -Cov- 2 IgG Antibody Test, COVID-19 Ab Detection+Measurement
5401080 50% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Covid Antibody IgG (Quantitative)


What is Covid Antibody IgG (Quantitative)?

The Covid Antibody IgG (Quantitative) test is a blood test that detects the presence and measures the levels of immunoglobulin G (IgG) antibodies produced by the immune system in response to the spike protein of coronavirus (SARS-CoV-2). It helps identify individuals who are suspected to have had coronavirus disease (COVID-19) or determine if they have developed immunity to the virus through vaccination. 

The Covid Antibody IgG (Quantitative) test helps confirm whether you have been previously infected with the coronavirus, even if you didn’t show symptoms or were not diagnosed at the time. It assesses whether you have developed antibodies after receiving a COVID-19 vaccine, indicating your level of immunity. Additionally, identifying individuals with antibodies against coronavirus, it helps understand the spread of the virus within communities and contributes to public health care strategies. 

Consider getting tested if you have a history of COVID-19 symptoms, such as fever, cough, or loss of taste and smell;  recent exposure to someone diagnosed with COVID-19; or post-vaccination to confirm antibody production. 

The Covid Antibody IgG (Quantitative) test offers several benefits. It can guide personal health decisions, such as taking additional precautions or understanding your risk level. It can help provide a clear picture of immunity status, which is required for certain travel destinations and employment. The test offers reassurance and clarity to those uncertain about their exposure to the virus or vaccination response. It helps monitor long-term immune response, which is especially important for at-risk individuals. For those with weak immune systems or underlying medical conditions, knowing antibody levels can help doctors tailor treatment plans. 

No special preparation is needed for the Covid Antibody IgG (Quantitative) test. However, this test is most effective when conducted between two to three weeks after the onset of COVID-19 symptoms or post-vaccination, allowing your body enough time to produce IgG antibodies in response to the infection.

Lab test results may vary across laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. Periodic testing may be recommended to monitor changes in antibody levels over time, especially for high-risk individuals. 

What is Covid Antibody IgG (Quantitative) used for?

The Covid Antibody IgG (Quantitative) test is done: 

  • To identify if you have had a previous COVID-19 infection (past infections). 
  • To assess if you have developed antibodies after receiving a COVID-19 vaccine.
  • To track how long antibodies last in your system (long-term immunity). 
  • If you have symptoms of COVID-19 infection, such as fever, shortness of breath, fatigue, sore throat, running nose, and loss of taste or smell.
  • To help understand the spread of the virus within communities.
  • To provide proof of immunity for travel or work-related purposes. 
  • To make informed decisions about your health and safety.

What does Covid Antibody IgG (Quantitative) measure?

The Covid Antibody IgG (Quantitative) test measures the levels (titers) of immunoglobulin G (IgG) antibodies in the blood which are produced by the immune system in response to COVID-19 infection. The presence of these antibodies indicates that you have been exposed to the coronavirus., either through infection or vaccination. By quantifying the amount of IgG antibodies, this test helps assess the strength and duration of your immune response. This information is important to understand your level of immunity and for making informed decisions about your health and safety. 

Interpreting Covid Antibody IgG (Quantitative) results


Interpretations

 

Measuring interval ranges from 21.0  AU/ml to 80,000 AU/mL.


< 50.0 AU/ml (Negative) - Indicates the absence of Anti-SARS-CoV-2 spike protein antibodies. However, It does not rule out the possibility of an infection with SARS-CoV-2.


   >=50.0 AU/ml (Positive) - Indicates presence of Anti-SARS-CoV-2 spike protein antibodies which indicates recent or past infection by the virus or vaccination.


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Covid Antibody IgG (Quantitative)


Frequently Asked Questions about Covid Antibody IgG (Quantitative)

Q. What is the Covid Antibody IgG (Quantitative) test?

The Covid Antibody IgG (Quantitative) test is a blood test that measures the levels of IgG antibodies specific to spike protein of the SARS-CoV-2 virus, which causes COVID-19. It helps determine whether an individual has been previously infected with the virus or has developed antibodies in response to vaccination.

Q. How is the Covid Antibody IgG (Quantitative) test performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Q. How accurate is the Covid Antibody IgG (Quantitative) test?

Generally, it is considered reliable for detecting past COVID-19 infection or immune response to the virus, but no test is 100% accurate. The accuracy of this test can vary depending on factors such as the quality of the test, the timing of the test relative to infection or vaccination, and individual variations in immune response.

Q. What do the Covid Antibody IgG (Quantitative) test results mean?

The quantitative result indicates the concentration or amount of IgG antibodies present in the blood sample. Higher antibody levels may suggest a stronger immune response to past infection or vaccination, while lower levels may indicate that an individual has not been exposed to the virus or has not developed a significant immune response probably due to a recent infection, waning immunity or an ineffective vaccination.

Q. What is the difference between the COVID-19 RT-PCR test and COVID-19 antibody test?

The COVID-19 RT-PCR test detects the presence of genetic material (RNA) of the coronavirus, indicating an active infection. In contrast, the COVID-19 antibody test detects the antibodies (specific proteins) produced by the immune system in response to the virus, indicating past exposure or vaccination.

Q. Can the Covid Antibody IgG (Quantitative) test be done at home?

Yes, Tata 1 mg labs offer safe and hygienic sample collection from the comfort of your home.
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Covid Antibody IgG (Quantitative) test price for other cities


Price inBangaloreRs. 550
Price inNew DelhiRs. 540
Price inPuneRs. 550
Price inHyderabadRs. 550
Price inKolkataRs. 540
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References

  1. Interim Guidelines for COVID-19 Antibody Testing [Internet]. CDC; 26 Aug. 2021 [Accessed 15 May. 2024]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/testing/antibody-tests-guidelines.html External Link
  2. McFee DRB. COVID-19 Laboratory Testing/CDC Guidelines. Dis Mon. 2020 Sep;66(9):101067. [Accessed 15 May. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409931/ External Link
  3. About COVID-19 [Internet]. CDC; 26 Aug. 2021 [Accessed 15 May 2024]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/your-health/about-covid-19.html External Link
  4. Kusunoki H, Ohkusa M, Iida R, Saito A, Kawahara M, Ekawa K, Kato N, Yamasaki K, Motone M, Shimizu H. Longitudinal Changes in IgG-Type SARS-CoV-2 Antibody Titers after COVID-19 Vaccination and a Prominent Increase in Antibody Titers When Infected after Vaccination. Vaccines (Basel). 2023 Apr 17;11(4):860. [Accessed 15 May. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145145/ External Link
  5. Ravi AB, Singh VPP, Chandran R, Venugopal K, Haridas K, Kavitha R. COVID-19 Antibody Tests: An Overview. J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S48-S51. [Accessed 15 May. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375937/ External Link
  6. Kumar D, Burma A, Mandal AK, Joshy V. A Comparative Analysis of COVID-19 IgG Antibody Level and Socio-Demographic Status in Symptomatic and Asymptomatic Population of South Andaman, India. Cureus. 2022 Feb 20;14(2):e22398. [Accessed 15 May. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938914/ External Link
  7. Hasan Z, Masood KI, Qaiser S, Khan E, Hussain A, Ghous Z, Khan U, Yameen M, Hassan I, Nasir MI, Qazi MF, Memon HA, Ali S, Baloch S, Bhutta ZA, Veldhoen M, Pedro Simas J, Mahmood SF, Ghias K, Hussain R. Investigating the impact of prior COVID-19 on IgG antibody and interferon γ responses after BBIBP-CorV vaccination in a disease endemic population: A prospective observational study. Health Sci Rep. 2023 Sep 8;6(9):e1521. [Accessed 15 May. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486204/#:~:text=We%20found%20that%20IgG%20seropositivity,observed%20earlier%20in%20unvaccinated%20individualsExternal Link

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