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FSH-LH-Testosterone

Also known as Hormonal profile, Hormonal panel
FSH-LH-Testosterone Includes 3 testsView All
12591608 21% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. In females, preferred sampling time is day 2 or 3 of menstrual cycle.

Understanding FSH-LH-Testosterone


What is FSH-LH-Testosterone?

An FSH-LH-Testosterone test helps assess hormonal balance and function in both men and women. These hormones play an important role in reproductive health, with Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) regulating the menstrual cycle in women and sperm production in men, while testosterone is primarily responsible for men's sexual characteristics and fertility. 

An FSH-LH-Testosterone test evaluates hormonal balance in the realm of reproductive health. It assesses three key hormones-Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), and testosterone. These hormones, produced by the pituitary gland and gonads (testes in men and ovaries in women), play pivotal roles in various physiological processes, important for reproductive and overall well-being. 

In women, FSH and LH help regulate the menstrual cycle. FSH helps eggs in the ovaries to grow, while LH triggers the release of mature eggs during ovulation. LH also helps produce progesterone, a hormone essential for maintaining pregnancy.  Monitoring FSH and LH levels tells about ovarian function, menstrual irregularities, and fertility. On the other hand, in men, FSH and LH are important for sperm production. FSH helps in the growth of sperm-producing structures, while LH stimulates testosterone production. Testosterone is a key hormone for the development of secondary sexual characteristics like deepening of voice, muscle growth, and facial and body hair in men. Also, this hormone helps maintain sexual desire, bone health, and overall vitality in men. 

An FSH-LH-Testosterone test is commonly suggested by a doctor to diagnose and monitor various reproductive disorders, such as polycystic ovary syndrome (PCOS), hypogonadism (low testosterone levels), and menstrual irregularities. By assessing the levels of FSH, LH, and testosterone, doctors can identify hormonal imbalances, guide treatment decisions, and monitor the effectiveness of interventions aimed at restoring hormonal balance and optimizing reproductive health. 

Usually, no special preparation is needed for an FSH-LH-Testosterone test. However,  in women, this test is advised on the second or third day of the menstrual cycle whereas for men, it can be done at any time. Additionally, you may discuss it with your doctor to temporarily stop taking certain medications or supplements, such as birth control pills, etc. as these may influence the test results. 

Lab test results may vary across different laboratories based on the different methodologies. Talk to your doctor about your specific test results. The results will help them evaluate your medical condition; make recommendations for diet, exercise, or medication; and formulate an overall treatment plan based on your condition. 

What is FSH-LH-Testosterone used for?

An FSH-LH-Testosterone test is done: 

  • To assess ovarian function in women.
  • To evaluate menstrual irregularities in women.
  • To investigate fertility problems in both men and women.
  • To monitor hormone levels during infertility treatments.
  • To diagnose and monitor conditions like Polycystic ovary syndrome (PCOS). 
  • To evaluate hypogonadism (low testosterone in men). 
  • To assess testicular function and sperm production in men. 
  • To investigate and monitor conditions affecting sexual development and puberty.
  • To monitor hormone levels during hormone replacement therapy. 

What does FSH-LH-Testosterone measure?

Contains 3 tests

An FSH-LH-Testosterone test measures the levels of three key hormones - follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone in the blood. These hormones are vital for hormonal function and overall reproductive health in both men and women. 

In females, FSH stimulates the growth and recruitment of immature ovarian follicles in the ovary. When the follicle matures and reaches 8–10 mm in diameter it starts to secrete significant amounts of estradiol. The sharp increase in estradiol production by the dominant follicle causes an LH surge. LH levels rise just before ovulation to trigger the release of a mature egg. This way, FSH levels help assess ovarian function in women. In males, FSH levels help assess testicular function. It helps in the growth of sperm-producing structures, while LH stimulates testosterone production.

Testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.

The levels of these hormones are typically low during younger ages. However, as adolescence approaches, the brain starts producing gonadotropin-releasing hormone (GnRH). GnRH stimulates the pituitary gland to release FSH and LH. These gonadotropin hormones play a crucial role in the production of sex hormones such as testosterone, which are responsible for initiating the changes of puberty and controlling reproductive function in both men and women. 

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Luteinising Hormone

The Luteinising Hormone test determines the level of luteinizing hormone that promotes the functioning of the gonads, i.e., testes in men and ovaries in women. LH is produced by the pituitary gland, a pea-sized gland situated at the base of the brain. The production and release of LH are controlled by a system known as the hypothalamic-pituitary-gonadal axis. A hormone called GnRH is released from the hypothalamus of the brain and binds to the cell receptors in the anterior pituitary gland, which in turn prompts the synthesis and release of luteinizing hormone. LH then travels across the blood and attaches to its target cells in the testes in men and ovaries in women to facilitate optimal sexual and reproductive activities.

Know more about Luteinising Hormone

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Follicle Stimulating Hormone

The Follicle Stimulating Hormone test measures the level of FSH in your body. FSH is produced and subsequently released into the blood by the pituitary gland. Its production is controlled by a feedback mechanism involving a hormone situated in the hypothalamus in the brain. The released FSH travels through your blood and then attaches to receptors in the ovaries and testes. It exerts functional effects on the reproductive organs, such as sexual development, puberty, and maturation. FSH levels vary throughout the menstrual cycle in response to estradiol and progesterone. Any disruption or issue in this feedback mechanism can prevent the normal function of the testicles or ovaries. Thus, determining its level provides crucial information regarding your health.

Know more about Follicle Stimulating Hormone

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Testosterone Total

The Testosterone Total test measures the level of testosterone hormone in the blood. Testosterone is a steroid hormone primarily produced in the testes in men, although it is also present in smaller quantities in the adrenal glands. In women, it is made in small amounts by the ovaries. It is predominantly associated with male physiology and significantly influences physiological functions in both men and women. 

The pituitary gland produces luteinizing hormone (LH), which regulates testosterone production. As testosterone levels rise, LH production decreases, slowing down testosterone production. Conversely, when testosterone levels fall, LH production increases, stimulating testosterone production.

Most of the testosterone circulating in the blood gets attached to two proteins, albumin and sex hormone-binding globulin (SHBG), and some of it remains unattached, called free testosterone. Free testosterone and albumin-bound testosterone are also known as bioavailable testosterone, as they are readily available for the body to use for proper functioning.

Know more about Testosterone Total

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about FSH-LH-Testosterone


Frequently Asked Questions about FSH-LH-Testosterone

Q. Why is an FSH-LH-Testosterone test done?

An FSH-LH-Testosterone test is done to assess the levels of hormones- FSH, LH, and testosterone that are essential for understanding reproductive health and fertility in both men and women.

Q. Is there any risk associated with an FSH-LH-Testosterone test?

There is usually no risk associated with this test. However, some people may feel a slight sting when a needle is pricked to collect a blood sample and may experience some bleeding that is normal and usually not bothersome.

Q. What factors can affect the levels of FSH, LH & testosterone?

Factors such as stress, physical activity, medications, and underlying health conditions can affect FSH, LH, and testosterone levels

Q. What are the symptoms of hormonal imbalance in women?

Women with hormonal imbalances often experience heavy or irregular periods, mood swings, raised blood sugar levels, bloating, fatigue, excessive facial hair growth, and unexplained weight changes.

Q. What are the symptoms of hormonal imbalance in men?

Men with hormonal imbalances may experience hair thinning, hair loss, weight gain/loss, low sex drive, erectile dysfunction, fatigue, and depression, and show poor semen parameters, including low sperm count, motility, and morphology, leading to infertility.

Q. Can levels of FSH vary during different days of the menstrual cycle?

Yes, FSH levels in women change throughout the menstrual cycle. Its levels peak during the menstruation and ovulatory phase and drop down during the late follicular and luteal phases of the menstrual cycle.

Q. What happens if the test results show high FSH levels in women?

High levels of FSH in women can indicate loss of ovarian function or ovarian failure, menopause, polycystic ovarian syndrome, chromosomal abnormalities (e.g., Turner's syndrome), and reduction in the production of good-quality eggs and embryos for fertilization.

Q. What are the causes of high levels of FSH in men?

High levels of FSH in men may indicate Klinefelter’s syndrome, absence of testicles or impaired functioning of testicles, damage to testicles by habits like alcohol dependence, or treatments such as X-rays or chemotherapy.

Q. What happens when LH levels are high?

In females, the rise in LH triggers ovulation and also affects progesterone levels. However, too high LH is associated with polycystic ovary syndrome and infertility. Further, high levels of LH cause early puberty, poor sperm morphology as well as motility, and indicate damaged testicles in males.

Q. What happens when LH levels are low?

Low LH levels can signify that your pituitary gland is not making sufficient LH which is needed to induce changes in your body that support sexual development or reproduction.

Q. What are the signs of low testosterone levels in men?

The signs of low testosterone levels in men include decreased muscle mass, lack of body and facial hair, very small testicles, and development of breast tissue.

Q. Will taking supplements help to raise testosterone levels?

While some supplements claim to boost testosterone levels, it's important to approach them with caution and should be taken after consulting your medical practitioner. The body regulates hormone levels, and altering them without medical advice may lead to unintended consequences. Before considering supplements, consult your doctor to ensure they are suitable and safe for your individual health condition.
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FSH-LH-Testosterone test price for other cities


Price inBangaloreRs. 1259
Price inNew DelhiRs. 1259
Price inHyderabadRs. 1259
Price inMumbaiRs. 1259
Price inPuneRs. 1259
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References

  1. Follicle-Stimulating Hormone [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 13 Mar. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=follicle_stimulating_hormone External Link
  2. Follicle stimulating hormone [Internet]. Healthdirect; [Accessed 13 Mar. 2024]. Available from: https://www.healthdirect.gov.au/follicle-stimulating-hormone#:~:text=Follicle%20stimulating%20hormone%20(FSH)%20is,of%20eggs%20by%20the%20ovaries. External Link
  3. Orlowski M, Sarao MS. Physiology, Follicle Stimulating Hormone [Internet]. Treasure Island, Florida: StatPearls Publishing; 2023 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK535442/ External Link
  4. O'Herlihy C, Pepperell RJ, Evans JH. The significance of FSH elevation in young women with disorders of ovulation. Br Med J. 1980 Nov 29;281(6253):1447-50. [Accessed 13 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1714809/ External Link
  5. Simoni M, Weinbauer GF, Gromoll J, Nieschlag E. Role of FSH in male gonadal function. Ann Endocrinol (Paris). 1999 Jul;60(2):102-6. [Accessed 13 Mar. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/10456180/#:~:text=In%20the%20male%20FSH%20is,maintenance%20of%20normal%20sperm%20production External Link
  6. Fortin J, Boehm U, Deng CX, Treier M, Bernard DJ. Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2. FASEB J. 2014 Aug;28(8):3396-410. [Accessed 13 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101660/ External Link
  7. Arslan AA, Zeleniuch-Jacquotte A, Lukanova A, Rinaldi S, Kaaks R, Toniolo P. Reliability of follicle-stimulating hormone measurements in serum. Reprod Biol Endocrinol. 2003 Jun 18;1:49. [Accessed 13 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165593/#:~:text=FSH%20levels%20peak%20during%20the,result%20of%20ovarian%20function%20cessation. External Link
  8. Behre HM. Clinical Use of FSH in Male Infertility. Front Endocrinol (Lausanne). 2019 May 24;10:322. [Accessed 13 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543808/#:~:text=In%20male%20infertility%2C%20the%20indication,with%20hypogonadotropic%20hypogonadism%20(1). External Link
  9. Luteinizing Hormone [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 13 Mar. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=luteinizing_hormone_blood External Link
  10. Kazmi SRH, Can AS. Luteinizing Hormone Deficiency. [Updated 2023 Sep 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK562219/ External Link
  11. Nedresky D, Singh G. Physiology, Luteinizing Hormone. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539692/ External Link
  12. Reed BG, Carr BR. The Normal Menstrual Cycle and the Control of Ovulation. [Updated 2018 Aug 5]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279054/ External Link
  13. Total Testosterone [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 13 Mar. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=testosterone_total External Link
  14. Low Testosterone [Internet]. Urology Care Foundation. [Accessed 13 Mar. 2024]. Available from: https://www.urologyhealth.org/urology-a-z/l/low-testosterone External Link
  15. Vesper H, Pirkle J. Total Testosterone-Laboratory Procedure Manual. CDC; [Accessed 13 Mar. 2024]. Available from: https://www.cdc.gov/nchs/data/nhanes/nhanes_11_12/tst_g_met.pdf External Link
  16. Rivas AM, Mulkey Z, Lado-Abeal J, Yarbrough S. Diagnosing and managing low serum testosterone. Proc (Bayl Univ Med Cent). 2014 Oct;27(4):321-4. [Accessed 13 Mar. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255853/ External Link
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