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An ESR test measures the rate at which red blood cells (erythrocytes) settle (sediment) in one hour at the bottom of a tube that contains a blood sample.

When there is inflammation in the body, certain proteins, mainly fibrinogen, increase in the blood. This increased amount of fibrinogen causes the red blood cells to form a stack (rouleaux formation) that settles quickly due to its high density, leading to an increase in the ESR.

An ESR test is a non-specific measure of inflammation and can be affected by conditions other than inflammation. This test cannot identify the exact location of the inflammation in your body or what is causing it. Hence, an ESR test is usually performed along with a few other tests to identify or treat possible health concerns.

The CBC (Complete Blood Count) test evaluates red blood cells (RBCs), white blood cells (WBCs}, and platelets. Each of these blood cells performs essential functions–RBCs carry oxygen from your lungs to the various body parts, WBCs help fight infections and other diseases, and platelets help your blood to clot–so determining their levels can provide significant health information. A CBC test also determines the hemoglobin level, a protein in RBC that carries oxygen from the lungs to the rest of your body. Evaluating all these components together can provide important information about your overall health.

This further contains

• Differential Leukocyte Count
• Red Blood Cell Count
• Hb (Hemoglobin)
• Platelet Count
• Total Leukocyte Count
• Hematocrit
• Mean Corpuscular Volume
• Mean Corpuscular Hemoglobin
• Mean Corpuscular Hemoglobin Concentration
• Absolute Leucocyte Count
• Mean Platelet Volume
• PDW
• RDW CV

The Vitamin B12 test measures your vitamin B12 levels. Vitamin B12 is essential for various health aspects, such as maintaining a healthy nervous system, making red blood cells, and creating the genetic material of our cells. Low vitamin B12 levels are more likely to occur in older adults, children, vegans, vegetarians, people with diabetes, individuals who underwent gastric bypass surgery, women who are breastfeeding, and in conditions that impact absorption of this vitamin, like Crohn’s disease. Higher vitamin B12 levels seen in pateint on vitamin suplement does not need treatment as excessive vitamin B12 is usually removed through the urine. However, some conditions, such as liver diseases and myeloproliferative disorders, can cause an increase in vitamin B12 levels, thereby affecting blood cell production.

The Vitamin D (25-Hydroxy) test measures the levels of vitamin D in the body. It is an essential nutrient that can be synthesized in the body upon healthy exposure to sunlight or absorbed from dietary sources. It majorly exists in two forms: Vitamin D2 (ergocalciferol) and Vitamin D3 (cholecalciferol). Vitamin D2 is present in plants, such as yeast or mushrooms, and is available as a supplement in fortified foods, and vitamin D3 is found in foods like cheese, green vegetables, mushrooms, egg yolks, and fatty fish.

Both forms of vitamin D (D2 and D3) need to undergo some chemical changes before being available for use in the body. These chemical changes take place in the liver or kidneys.The levels of 25-hydroxy Vitamin D in blood is considered the best parameter to assess vitamin D status of the body. A Vitamin D (25-Hydroxy) measures the level of Total 25-OH vitamin D (D2+D3) , but it does not differentiate between the two forms as it is the major form of vitamin D that circulates in the blood.