
Hemoglobin HPLC / Electrophoresis near me in Indore









An Hemoglobin HPLC / Electrophoresis test is a specialized test used to identify and quantify normal and abnormal forms of hemoglobin in the blood. It is available at an affordable price in Indore with Tata 1mg Labs. Hemoglobin (Hb) is an iron-rich protein that carries oxygen to organs and tissues. An Hemoglobin HPLC / Electrophoresis test helps identify hemoglobin variants, such as HbA, HbD, and HbF, crucial for diagnosing conditions marked by abnormal hemoglobin production like thalassemia and anemia. It is valuable for individuals undergoing treatments like transfusions in cases of unexplained anemia or familial blood disorder history, enabling doctors to assess treatment effectiveness.
Your doctor may suggest an Hb HPLC test when a blood disorder such as thalassemia or sickle cell disease is suspected. Fasting is not required for an Hemoglobin HPLC / Electrophoresis test; you can eat and drink normally per your daily routine. Inform your doctor if you recently underwent a blood transfusion, which may impact the test results.








What does Hemoglobin HPLC / Electrophoresis measure?
The Hemoglobin HPLC / Electrophoresis test identifies and measures different types of hemoglobin in the blood to help diagnose and keep track of certain blood disorders. These types include: adult type (HbA2), fetal type (HbF), hemoglobin S (HbS), hemoglobin C (HbC), and hemoglobin E (HbE), among others.
Normal hemoglobin types:
- Hemoglobin A (HbA): The main type of hemoglobin in healthy adults.
- Hemoglobin F (HbF): Found in unborn babies and newborns. It is slowly replaced by HbA after birth.
If the levels of HbA or HbF are not normal, it may indicate certain types of anemia.
Abnormal hemoglobin types:
- Hemoglobin S (HbS): Found in people with sickle cell anemia. It causes red blood cells to become stiff and sickle-shaped, leading to pain and other health problems.
- Hemoglobin C (HbC): Linked to a condition called hemolytic anemia, where red blood cells break down faster than normal.
- Hemoglobin E (HbE): Common in people from Southeast Asia. It may cause mild anemia or sometimes no symptoms at all.
- Hemoglobin D (HbD): Causes mild hemolytic anemia and mild to moderate spleen enlargement. The Hb D Punjab variant is most commonly seen in people from Gujarat and among Sikhs of Punjab.





FAQs related to Hemoglobin HPLC / Electrophoresis in Indore
- Wajcman H, Moradkhani K. Abnormal haemoglobins: detection & characterization. Indian J Med Res. 2011 Oct;134(4):538-46. PMID: 22089618; PMCID: PMC3237254. [Accessed 30 Oct. 2023]. Available from:
- Kohne E. Hemoglobinopathies: clinical manifestations, diagnosis, and treatment. Dtsch Arztebl Int. 2011 Aug;108(31-32):532-40. [Accessed 30 Oct. 2023]. Available from:
- Forget BG, Bunn HF. Classification of the disorders of hemoglobin. Cold Spring Harb Perspect Med. 2013 Feb 1;3(2):a011684. [Accessed 30 Oct. 2023]. Available from:
- Khera R, Singh T, Khuana N, Gupta N, Dubey AP. HPLC in characterization of hemoglobin profile in thalassemia syndromes and hemoglobinopathies: a clinicohematological correlation. Indian J Hematol Blood Transfus. 2015 Mar;31(1):110-5. [Accessed 30 Oct. 2023]. Available from:
- What is Thalassemia? [Internet]. CDC; 24 April 2023; [Accessed 30 Oct. 2023]. Available from:
- What is Sickle Cell Disease? [Internet]. CDC; 06 July 6 2023; [Accessed 30 Oct. 2023]. Available from:
- Billett HH. Hemoglobin and Hematocrit. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 151. Available from:
- Ahmed MH, Ghatge MS, Safo MK. Hemoglobin: Structure, Function and Allostery. Subcell Biochem. 2020;94:345-382. [Accessed 30 Oct. 2023]. Available from:
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