Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
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References
Other Tests
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Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
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HSV 2, IgG & IgM

Also known as Herpes Simplex Virus Type 2 IgM & IgG Antibody test
HSV 2, IgG & IgM Includes 2 testsView All
12591400 10% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding HSV 2, IgG & IgM


What is HSV 2, IgG & IgM?

The HSV 2, IgG & IgM test is a blood test done to detect the presence of immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies against herpes simplex virus (HSV) type 2, known to cause primarily genital herpes. This test helps determine the stage of the infection, differentiate between recent (acute) and past (chronic) infections, and aid in the timely management of the infection.

Herpes simplex virus (HSV) infection (herpes) is a skin infection that may spread through sexual contact or skin-to-skin contact with an infected person. HSV-2 primarily causes genital herpes,which  is characterized by painful sores and blisters in the genital and anal area. 

The HSV 2, IgG & IgM test measures two types of antibodies: Immunoglobulin G (IgG) and Immunoglobulin M (IgM) produced as an immune response against HSV-2. IgM antibodies suggest a recent or acute infection, as they are produced early in the immune response and usually decline after a few months. IgG antibodies indicate past or chronic infection with the virus, as they typically develop after the initial infection and persist for life.

This test is often recommended when an individual exhibits symptoms suggestive of genital herpes, such as sores or blisters around genital and anal area, recurring blisters or ulcers, pain during urination, unusual discharge from the urethra and vagina, fever, body aches, etc. This test can also be done as part of routine screenings for sexually transmitted infections (STIs) or pre-pregnancy check-ups, as HSV-2 can be transmitted to the baby during childbirth. 

No specific preparation is needed to get the HSV 2, IgG & IgM test done. You can eat and drink normally before the test. Talk to your doctor about your specific test results. Narrate your complete medical history and symptoms to help them correlate your clinical and laboratory findings and formulate your treatment plan.

What is HSV 2, IgG & IgM used for?

The HSV 2, IgG & IgM test is done: 

  • To confirm the diagnosis of herpes simplex virus (HSV) 2 infection in individuals with suggestive symptoms.
  • To find out if an individual has recently or previously (in the past) been exposed to herpes infection.
  • For individuals experiencing symptoms of herpes, such as cold or genital sores, or those who have been exposed to the virus and wish to know their infection status.
  • As a screening test during pregnancy to prevent neonatal herpes. 

What does HSV 2, IgG & IgM measure?

Contains 2 tests

The HSV 2, IgG & IgM test is a blood test used to measure two types of antibodies: Immunoglobulin G (IgG) and Immunoglobulin M (IgM) against herpes simplex virus (HSV) type 2. IgG antibodies indicate a past infection or long-term presence of the virus, while IgM antibodies suggest a recent or acute infection. By identifying these antibodies, this test helps determine if an individual has been exposed to the virus and distinguishes between new and existing infections.

Early and precise identification of HSV infections allows timely medical intervention, reducing symptoms and preventing complications. For pregnant women, detecting an HSV infection is crucial to prevent neonatal herpes, which can be severe for newborns. Additionally, knowing one's HSV status helps in taking preventive measures to avoid transmission to sexual partners and others, thus playing a significant role in public health and personal well-being.

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Herpes Simplex Virus 2, IgG

The Herpes Simplex Virus 2, IgG test looks for the presence of IgG antibodies against HSV-2  in response to the Herpes infection. IgG antibodies are the most frequent type of antibody, which are developed around 18 to 21 days after the virus invades the body and remains in the body for life. Thus, the presence of IgG antibodies typically means an individual has been infected with the HSV-2 at some point. Detection of HSV-2 infection allows doctors to provide necessary support and guidance to individuals suffering from genital herpes, leading to better treatment outcomes and improved quality of life.

Know more about Herpes Simplex Virus 2, IgG

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Herpes Simplex Virus 2, IgM

The Herpes Simplex Virus 2, IgM test detects the presence of IgM antibodies that are produced against an infection caused by herpes simplex virus 2 (HSV-2). IgM antibodies specific for HSV-2 are present only for a relatively short period of time. They are the first antibodies to form after the infection and are excellent markers for the presence of a recently acquired or active disease. Also, these antibodies are usually present in higher concentrations shortly after infection and eventually decrease after some time (7-10 days).

Know more about Herpes Simplex Virus 2, IgM

Interpreting HSV 2, IgG & IgM results


Interpretations

 

  • A positive HSV-2 IgM test indicates recent or active infection.

• A positive HSV-2 IgG test indicates previous infection.
• A significant increase in HSV 2 IgG antibodies also indicates an active or recent infection.
• Negative results indicate that no exposure to HSV occurred, or that antibodies were not yet produced.

 

 

 

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about HSV 2, IgG & IgM


Frequently Asked Questions about HSV 2, IgG & IgM

Q. What is the purpose of the HSV 2, IgG & IgM test?

The HSV 2, IgG & IgM test detects antibodies in the blood that indicate a past or recent genital herpes infection. The presence of IgG antibodies suggests a past infection, while the presence of IgM antibodies indicates a recent or active infection.

Q. When should I get tested for the HSV 2, IgG & IgM test?

You should consider getting tested if you have symptoms of genital herpes (such as bumps, blisters, or open sores (ulcers) around the genital and anal areas or if you have had sexual contact with someone who has herpes, or if you are pregnant and have a history of herpes.

Q. Can asymptomatic individuals test positive for HSV-2 IgM or IgG?

Yes, individuals who are asymptomatic can test positive for both HSV-2 IgM and IgG. A positive IgM test indicates a recent infection, even if no symptoms are present, making testing important for high-risk individuals regardless of symptom presence. Similarly, a positive IgG test signifies past exposure to the virus, reflecting previous infection even in the absence of current symptoms. Testing is essential for accurate diagnosis and understanding of HSV status, regardless of whether symptoms are evident.

Q. What is the difference between HSV 2 IgG and IgM?

The HSV-2 IgM test detects recent infections by identifying early antibodies produced shortly after exposure to the virus. In contrast, the HSV-2 IgG test identifies past infections through antibodies that develop later and remain in the body for long-term. Thus, IgM indicates recent infection, while IgG shows past exposure and long-term immunity.

Q. What precautions can help in preventing HSV infections?

Practicing safe sex, avoiding close physical contact with infected individuals, and maintaining good personal hygiene can help prevent the spread of HSV.

Q. How is herpes managed?

Herpes can be well managed with antiviral medications, especially during outbreaks. It is advised to take only prescribed medicines and not self-medicate.

Q. How can I reduce the risk of transmission?

Use condoms, take antiviral medication if prescribed, avoid sexual contact during outbreaks, and practice good hygiene to reduce the risk of transmitting HSV.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
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HSV 2, IgG & IgM test price for other cities


Price inBangaloreRs. 1259
Price inNew DelhiRs. 1259
Price inNoidaRs. 1330
Price inHyderabadRs. 1259
Price inGreater NoidaRs. 1330
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References

  1. Genital Herpes – CDC Basic Fact Sheet [Internet]. CDC; 03 Jan. 2022 [Accessed 06 Aug. 2024]. Available From: https://www.cdc.gov/std/herpes/stdfact-herpes.htm#:~:text=While%20herpes%20is%20not%20curable,your%20concerns%20and%20treatment%20options. External Link
  2. Genital Herpes Screening FAQ [Internet]. CDC; 11 Jul. 2022 [Accessed 06 Aug. 2024]. Available from: https://www.cdc.gov/std/herpes/screening.htm External Link
  3. Herpes simplex virus [Internet]. WHO; 05 Apr. 2023 [Accessed 06 Aug. 2024]. Available from: https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus External Link
  4. Tada DG, Khandelwal N. Serum HSV-1 and 2 IgM in Sexually Transmitted Diseases - More for Screening Less for Diagnosis: An Evaluation of Clinical Manifestation. J Glob Infect Dis. 2012 Jul;4(3):S1-4. [Accessed 06 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459440/ External Link
  5. Nath P, Kabir MA, Doust SK, Ray A. Diagnosis of Herpes Simplex Virus: Laboratory and Point-of-Care Techniques. Infect Dis Rep. 2021 Jun 2;13(2):518-539. [Accessed 06 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293188/ External Link
  6. Sauerbrei A. Herpes Genitalis: Diagnosis, Treatment and Prevention. Geburtshilfe Frauenheilkd. 2016 Dec;76(12):1310-1317. [Accessed 06 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177552/ External Link
  7. Katz D, Hilliard JK, Mirkovic RR, Word RA. ELISA for detection of IgG and IgM antibodies to HSV-1 and HSV-2 in human sera. J Virol Methods. 1986 Aug;14(1):43-55. [Accessed 06 Aug. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/3021796/ External Link

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