Infertility Panel for Women near me in Pune

A Dehydroepiandrosterone Sulphate test measures the levels of dehydroepiandrosterone sulphate (DHEAS) in the blood. DHEAS is a steroid hormone that is present in both males and females. It is primarily produced by the adrenal glands, with smaller amounts produced by ovaries in females and testicles in males. 

DHEAS plays a role in developing male secondary sexual characteristics at puberty. The body can convert it into more potent androgens like testosterone and androstenedione. Also, it can be converted into the female hormone estrogen. 

A Dehydroepiandrosterone Sulphate test helps diagnose and differentiate certain endocrine disorders, contributing to a comprehensive understanding of hormonal balance in the body.

An AMH (Anti-Mullerian Hormone) test evaluates the amount of AMH available in your body. AMH is produced by the granulosa cells of the ovarian follicles in females and the Sertoli cells of the testes in males. During the early development of a baby boy, AMH levels are high, which inhibits the development of female reproductive organs while promoting the development of male reproductive organs. On the contrary, in a girl child, low levels of AMH are produced, thus allowing the development of female reproductive structures. The AMH level in young girls remains low until puberty but increases significantly, reaching a peak in early adulthood. AMH levels tend to decrease with age and are undetectable in postmenopausal women.

AMH plays a vital role in developing ovarian follicles in women and is considered an important marker of ovarian reserve, which can be essential in assessing fertility. In men, this hormone is involved in the development and functioning of the testes. Measuring AMH levels in the blood provides critical information about reproductive health in both men and women, which can help assess fertility and guide treatment.

An E2 (Estradiol) test measures estradiol levels, a hormone produced in men and women. It helps assess early or delayed puberty, menstrual problems, symptoms associated with menopause, or certain cancers like ovarian cancer. This test provides valuable information about ovarian function and aids doctors in evaluating menstrual issues, such as abnormal bleeding or missed periods. The test can also assess the health of the testes, ovaries, or adrenal glands. Most diseases associated with estrogen/estradiol, such as PCOS, infertility, some cancers, etc., can be prevented by lifestyle modifications, menopausal hormone therapy, or other supplements such as calcium, vitamin D, and micronutrients.

The Follicle Stimulating Hormone test measures the level of FSH in your body. FSH is produced and subsequently released into the blood by the pituitary gland. Its production is controlled by a feedback mechanism involving a hormone situated in the hypothalamus in the brain. The released FSH travels through your blood and then attaches to receptors in the ovaries and testes. It exerts functional effects on the reproductive organs, such as sexual development, puberty, and maturation. FSH levels vary throughout the menstrual cycle in response to estradiol and progesterone. Any disruption or issue in this feedback mechanism can prevent the normal function of the testicles or ovaries. Thus, determining its level provides crucial information regarding your health.

The Serum Prolactin test measures the levels of prolactin hormone in a person’s body. During pregnancy, prolactin, estrogen, and progesterone hormones stimulate breast milk development. Following childbirth, prolactin helps initiate and maintain the breast milk supply. If a woman does not breastfeed, her prolactin concentration will soon drop back to pre-pregnancy levels.

Besides pregnancy, the most common cause of elevated prolactin concentration is prolactinoma, a prolactin-producing tumor of the pituitary gland. Prolactinomas are the most common type of pituitary tumor and are usually benign (non-cancerous). They develop more frequently in women but are also found in men.

If the pituitary gland and/or the tumor enlarge significantly, it can put pressure on the optic nerve, causing headaches and visual disturbances, and can interfere with the other hormones that the pituitary gland produces.

The TSH (Thyroid Stimulating Hormone) Ultrasensitive test measures the levels of TSH hormone in the blood. TSH is produced by the pituitary gland located in the brain. Its function is to stimulate and regulate the functioning of the thyroid gland. It signals the thyroid gland to increase or decrease the production of thyroid hormones T3 and T4 (essential for regulating our body’s metabolism, temperature, heart rate, and growth) when their levels are low or high, respectively. Therefore, when the levels of T3 & T4 decrease, the pituitary gland is stimulated to release TSH. This high TSH level, in turn, stimulates the thyroid gland to release more thyroid hormones (T3 & T4); the vice-versa happens when the levels of thyroid hormones increase.

The Luteinising Hormone test determines the level of luteinizing hormone that promotes the functioning of the gonads, i.e., testes in men and ovaries in women. LH is produced by the pituitary gland, a pea-sized gland situated at the base of the brain. The production and release of LH are controlled by a system known as the hypothalamic-pituitary-gonadal axis. A hormone called GnRH is released from the hypothalamus of the brain and binds to the cell receptors in the anterior pituitary gland, which in turn prompts the synthesis and release of luteinizing hormone. LH then travels across the blood and attaches to its target cells in the testes in men and ovaries in women to facilitate optimal sexual and reproductive activities.

The Testosterone Total test measures the level of testosterone hormone in the blood. Testosterone is a steroid hormone primarily produced in the testes in men, although it is also present in smaller quantities in the adrenal glands. In women, it is made in small amounts by the ovaries. It is predominantly associated with male physiology and significantly influences physiological functions in both men and women. 

The pituitary gland produces luteinizing hormone (LH), which regulates testosterone production. As testosterone levels rise, LH production decreases, slowing down testosterone production. Conversely, when testosterone levels fall, LH production increases, stimulating testosterone production.

Most of the testosterone circulating in the blood gets attached to two proteins, albumin and sex hormone-binding globulin (SHBG), and some of it remains unattached, called free testosterone. Free testosterone and albumin-bound testosterone are also known as bioavailable testosterone, as they are readily available for the body to use for proper functioning.