Quadruple Marker with Graph - 2nd Trimester near me in Thane
Understanding Quadruple Marker with Graph - 2nd Trimester in Thane
What is Quadruple Marker with Graph - 2nd Trimester in Thane?
A Quadruple Marker with Graph - 2nd Trimester is a prenatal screening test typically conducted between the 14th and 22nd weeks (ideal 15-20 weeks, i.e., second trimester) of pregnancy. It tells about the risk of specific chromosomal abnormalities, such as Down syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), neural tube defects (such as spina bifida), and anencephaly (a brain defect) in the fetus. It is widely available with Tata 1mg labs at an affordable price in Thane.
This test measures the levels of four specific biomarkers in the mother’s blood: Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Unconjugated Estriol (uE3), and Inhibin A. The levels of these markers, when assessed collectively along with maternal age, gestational age, and ultrasound findings, help determine the likelihood of certain fetal abnormalities that can affect the baby’s growth and development.
In addition to the traditional Quad marker analysis, the inclusion of a graphical representation enhances the interpretability of results.
No special preparation is required before undergoing a Quadruple Marker with Graph - 2nd Trimester test. However, a woman needs to provide informed consent before undertaking this test. The laboratory personnel will explain the purpose, benefits, and limitations of this test.
What does Quadruple Marker with Graph - 2nd Trimester measure?
Contains 4 testsA Quadruple Marker with Graph - 2nd Trimester test measures the levels of four specific markers in a pregnant woman's blood. These markers are -Alpha-Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Unconjugated Estriol, and Inhibin-A.
The analysis of these four markers and other factors like maternal age and gestational age helps assess the risk of certain conditions in the developing baby. The graph in a Quadruple Marker with Graph - 2nd Trimester provides a visual representation of the levels of these markers during pregnancy.
It is noteworthy that a Quadruple Marker with Graph - 2nd Trimester is a screening test, and any abnormal results may prompt further diagnostic testing for confirmation. Pregnant women should discuss their results and implications with their doctor.
Inhibin A
The Inhibin A test measures the level of inhibin A in the blood. It is a hormone primarily produced by the ovaries in women. It plays a key role in regulating menstrual cycle and ovarian function by inhibiting the production of follicle-stimulating hormone (FSH). During pregnancy, elevated levels of Inhibin A may point towards a risk of certain chromosomal abnormalities like Down’s syndrome etc., in the fetus.
The Inhibin A test is particularly useful in assessing ovarian function, fertility assessment, prenatal screening and diagnosing certain ovarian cancers.
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HCG Beta Total Quantitative, Maternal
An HCG Beta Total Quantitative, Maternal test measures the levels of human chorionic gonadotropin (hCG) hormone in the blood. hCG is released in the blood during pregnancy and can be detected as early as 10 days after conception. The levels of this hormone gradually rise every 2 to 3 days (or 48 to 72 hours) and peak around 8 to 11 weeks after conception. After reaching the peak, the hCG levels decrease and remain steady for the rest of the pregnancy.
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Unconjugated Estriol
The Unconjugated Estriol test is used to measure Unconjugated Estriol (uE3), a type of estrogen that is particularly significant during pregnancy. It is produced by both the fetus and the placenta. The levels of uE3 in the mother's blood can give insights into the baby's well-being and can be crucial for identifying certain risks and complications in pregnancy.
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Alpha Feto Protein, Maternal
An Alpha Feto Protein, Maternal test measures the amount of Alpha Fetoprotein in expectant mothers usually during the second trimester (14th and 22nd weeks). AFP is a protein produced by the fetus, primarily by the fetal liver and yolk sac, and it passes into the mother's blood. The test is typically performed to screen for certain fetal abnormalities, particularly neural tube defects (NTDs) such as spina bifida and anencephaly, as well as chromosomal abnormalities like Down syndrome (trisomy 21), Edwards syndrome (Trisomy 18), etc.
Detecting these abnormalities early in pregnancy allows for appropriate medical management and intervention.
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Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Quadruple Marker with Graph - 2nd Trimester in Thane
Frequently Asked Questions about Quadruple Marker with Graph - 2nd Trimester in Thane
Q. What is a Quadruple Marker with Graph - 2nd Trimester test, and why is it important?
Q. What tests are done in a quad marker test?
Q. When can I go for a quad marker test during my pregnancy?
Q. How is a quad marker test performed, and is it safe for the baby?
Q. What chromosomal abnormalities are screened by a quad marker test?
Q. Does Tata 1mg Labs offer a quad marker test in Thane near me?
Q. Is home sample collection facility available for a quad marker test in Thane with Tata 1mg Labs?
Q. How can I schedule a quad marker test with Tata 1mg Labs in Thane?
Q. What is the price of a quad marker test at Tata 1mg Labs in Thane?
Q. How can I get my quad marker test report from Tata 1mg?
Q. What is the estimated turnaround time for the results of a quad marker test in Thane?
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References
- Greene ND, Copp AJ. Neural tube defects. Annu Rev Neurosci. 2014;37:221-42. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486472/#:~:text=Neural%20tube%20defects%20(NTDs)%2C,both%20genetic%20and%20environmental%20factors.
- Screening for Down's syndrome, Edwards' syndrome and Patau's syndrome [Internet]. NHS; 19 April 2021 [Accessed 20 Dec. 2023]. Available from: https://www.nhs.uk/pregnancy/your-pregnancy-care/screening-for-downs-edwards-pataus-syndrome/#:~:text=Combined%20test-,A%20screening%20test%20for%20Down's%20syndrome%2C%20Edwards'%20syndrome%20and%20Patau's,as%20the%2012%2Dweek%20scan.
- Sablok A, Sharma A, Ahmed CS, Kaul A. Performance of second-trimester maternal biochemistry screening (quadruple test vs. triple test) for trisomy 21: An Indian experience. Indian J Med Res. 2021 May;154(5):716-722. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210531/
- Gordon S, Umandap C, Langaker MD. Prenatal Genetic Screening. [Updated 2023 Jan 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557702/
- Güdücü N, Görmüş U, Güner Eİ, Güzel O, Kavak ZN. Quadruple test parameters in art pregnancies. Int J Clin Exp Med. 2014 Aug 15;7(8):2319-23. PMID: 25232428; PMCID: PMC4161588. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161588/
- Commit to Healthy Choices to Help Prevent Birth Defects [Internet]. CDC; 28 June 2023 [Accessed 20 Dec. 2023]. Available from: https://www.cdc.gov/ncbddd/birthdefects/prevention.html
- Institute of Medicine (US) Committee on Improving Birth Outcomes; Bale JR, Stoll BJ, Lucas AO, editors. Reducing Birth Defects: Meeting the Challenge in the Developing World. Washington (DC): National Academies Press (US); 2003. 3, Interventions to Reduce the Impact of Birth Defects. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK222083/
- Boonpiam R, Wanapirak C, Sirichotiyakul S, Sekararithi R, Traisrisilp K, Tongsong T. Quad test for fetal aneuploidy screening as a predictor of small-for-gestational age fetuses: a population-based study. BMC Pregnancy Childbirth. 2020 Oct 15;20(1):621. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559175/
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