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Sex Hormone Binding Globulin

Also known as Testosterone-estrogen Binding Globulin

₹2250~~₹2500~~ 10% Off

You need to provide

Blood

This test is for

Male, Female

Test Preparation

No special preparation is required.

Understanding Sex Hormone Binding Globulin

What is Sex Hormone Binding Globulin?

The Sex Hormone Binding Globulin is a blood test that measures the level of sex hormone binding globulin (SHBG), a protein made mostly in the liver. It binds to three sex hormones: testosterone, dihydrotestosterone (DHT), and estrogen. This test is usually done in both men and women when there are signs and symptoms of having too much or too little of the sex hormone testosterone.

The Sex Hormone Binding Globulin test helps evaluate men for low testosterone and women for excess testosterone production. It provides valuable insights into hormone balance and can help diagnose various conditions related to hormonal imbalances, such as hypogonadism, hyperthyroidism, polycystic ovarian syndrome (PCOS) ,and hirsutism. Additionally, it can help assess the effectiveness of hormone replacement therapy (HRT) and monitor treatment response.

The Sex Hormone Binding Globulin test can be done in conjunction with other hormonal tests such as a total and free testosterone test to evaluate the status of your sex hormones.

SHBG is a vital protein that helps regulate the sex hormones, primarily testosterone, DHT and estrogen. Measuring SHBG levels can provide information about how much of your testosterone is active in the tissues of your body. In adult males, testosterone controls sex drive, maintains muscle mass, and helps make sperm. In adult females, testosterone is important for healthy organs and the growth of bones and muscles.

Too little testosterone in males and too much testosterone in females can cause problems. Moreover, the level of SHBG in your blood changes because of factors such as sex and age. It can also change because of obesity, liver disease, and hyperthyroidism.

No special preparation is required for the Sex Hormone Binding Globulin test; you can eat or drink as per your daily routine. However, It is important to inform your doctor about any medications, supplements, or medical conditions you may have, as these factors could potentially affect the test results.

Lab test results may vary across laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.

What is Sex Hormone Binding Globulin used for?

The Sex Hormone Binding Globulin test is done:

To assess the levels of testosterone and estrogen in the blood
To help diagnose androgen-related conditions such as hypogonadism, polycystic ovarian syndrome, and thyroid disorders
To investigate symptoms of hormonal imbalance such as irregular menstrual cycles, decreased sex drive, infertility, excess facial and body hair (hirsutism), acne etc in both men and women
To monitor the effectiveness of hormonal replacement therapy(HRT) or other treatments affecting hormone levels
In conjunction with other hormonal tests to evaluate the status of your sex hormones

What does Sex Hormone Binding Globulin measure?

The Sex Hormone Binding Globulin test measures the level of sex hormone binding globulin (SHBG) protein in the blood and is most often used to help evaluate you for testosterone deficiency or excess. SHBG is produced by the liver and it helps in the transport and regulation of sex hormones, primarily testosterone, dihydrotestosterone (DHT) and estrogen.

When the SHBG protein binds to sex hormones, your tissues can't use those hormones. Your tissues can only use sex hormones that are "free," which means they aren't attached to proteins, such as SHBG. Changes in SHBG levels can affect the amount of hormone used by the body’s tissues.

In men, SHBG binds to sex hormones like testosterone and regulates their levels in the blood. When SHBG levels are higher , less free testosterone is available for the body to use. However, when SHBG levels are lower, more free testosterone is available. This balance is important for maintaining overall health and hormonal function in men.

In women, SHBG plays an integral role in regulating the levels of bioavailable male sex hormones (androgens) and estrogens circulating throughout the body. SHBG has a higher affinity for the androgens testosterone and DHT, and so with the low SHBG, women may have signs and symptoms related to androgen excess.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Sex Hormone Binding Globulin

Frequently Asked Questions about Sex Hormone Binding Globulin

Q. What is the Sex Hormone Binding Globulin test?

The Sex Hormone Binding Globulin test is a blood test that helps evaluate the levels of Sex Hormone Binding Globulin(SHBG). It is a protein that binds to sex hormones , like testosterone and estrogen,regulating their availability in the body. This test helps assess hormonal balance and diagnose conditions affecting the hormonal balance such as hypogonadism, Polycystic ovarian syndrome (PCOS) etc.

Q. Why do I need the Sex Hormone Binding Globulin test?

You may need the Sex Hormone Binding Globulin test to help diagnose conditions related to hormonal imbalances, such as low testosterone levels in men or excessive facial and body hair growth in women. It can also help in evaluating unexplained symptoms like excessive fatigue, infertility or sexual dysfunction.

Q. How often should I book the Sex Hormone Binding Globulin test ?

The frequency of testing depends on your individual health condition, risk factors and symptoms that you might have. However, it is best to follow your doctor's recommendations.

Q. What are the risks associated with the Sex Hormone Binding Globulin test?

The risks associated with this test are generally minimal. However, some people may experience mild pain or discomfort at the site from where the blood sample is taken, which is usually self-limiting.

Q. What precautions should I take before and after the Sex Hormone Binding Globulin test?

Before the test, follow your doctor’s instructions about avoiding certain medications or supplements , as these can affect the results. After the test, you can resume your normal activities immediately.

Q. What additional tests can be advised along with the Sex Hormone Binding Globulin test?

The additional tests may vary as per your doctor’s discretion. However, commonly prescribed tests include total and free testosterone test, estrogen test, androgen index test, thyroid profile etc.

Q. What can I do to increase SHBG levels?

Always consult your doctor for personalized advice. However, adopting certain measures such as maintaining a healthy body weight, engaging in regular physical activity, considering a balanced diet rich in nutrients and low in processed foods , avoiding alcohol and managing underlying conditions such as thyroid, diabetes may help support SHBG levels.