Total Leukocyte Count
Understanding Total Leukocyte Count
What is Total Leukocyte Count?
The Total Leukocyte Count, also known as TLC test measures the number of leukocytes, also known as white blood cells (WBCs), in the blood. This test helps detect infection, inflammation, and bone marrow disorders. It is often done as part of a complete blood count test that also measures other types of blood cells.
Leukocytes or WBCs are white-colored blood cells that are a part of the immune system and defend the body against infections and diseases. There are five types of WBCs, namely basophils, eosinophils, lymphocytes, monocytes, and neutrophils, and each one supports the immune system differently.
A decrease in the TLC count is referred to as leukopenia and indicates a decline in the body’s ability to fight infections. Whereas, an increase in TLC, known as leukocytosis, indicates acute infections and inflammation. Your doctor may advise the Total Leukocyte Count test if you show symptoms suggestive of an infection, inflammation, or other health conditions like bone marrow disorders. However, this test is followed up with other tests to determine the exact cause of the abnormal results. A TLC test is also used to monitor your response to medical treatments that can affect the immune system, including chemotherapy which is known to affect the number of leukocytes. No special preparation is needed for a TLC test; eat or drink normally as per your daily routine.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. The test results will help your doctor determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your condition and formulate your overall treatment plan.
What is Total Leukocyte Count used for?
The Total Leukocyte Count test can be done:
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As a part of routine checkups to monitor your overall health.
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As a part of a complete blood count (CBC) test.
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To help detect conditions that decrease WBC count, like bone marrow disorders.
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To help detect infections and inflammation.
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To monitor the response to certain medical treatments that can affect the immune system, including chemotherapy.
What does Total Leukocyte Count measure?
The Total Leukocyte Count test measures the numbers of all types of leukocytes, namely neutrophil, lymphocyte, monocyte, eosinophil, and basophil, in your blood. Leukocytes or WBCs are an essential part of our immune system. These cells are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.
Interpreting Total Leukocyte Count results
Interpretations
Normal range (Approx.):
· Newborns: 9,000 to 30,000/mm3
· Children below 2 years of age: 6,200 to 17,000/ mm3
· Children over 2 years of age and adults: 5,000 to 10,000/ mm3
Note: Normal range of leukocyte count depends on several factors apart from age, including gender, health condition, previous instance of diseases, vaccinations, etc. The range also varies slightly between different laboratories performing the test.
A higher-than-normal leukocyte count indicates an infection or inflammation being treated by the body.
A lower-than-normal leukocyte count indicates improper functioning of the immune system.
Leukocyte Count Test is to be followed up with other tests to determine the exact cause of the abnormal results, if any.