Triple Marker with Graph, 2nd Trimester near me in Kolkata
Understanding Triple Marker with Graph, 2nd Trimester in Kolkata
What is Triple Marker with Graph, 2nd Trimester in Kolkata?
The Triple Marker with Graph, 2nd Trimester test is a prenatal screening test typically conducted between 14-22 weeks of gestation, ideally between 15-20 weeks (the second trimester) of pregnancy, and tells about the risk of specific chromosomal abnormalities, such as Down syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), neural tube defects (such as spina bifida) and anencephaly (a brain defect) in the fetus.
It measures the levels of three biomarkers in the mother’s blood: Alpha-fetoprotein (AFP), Human chorionic gonadotropin (HCG), and unconjugated Estriol (uE3). The levels of these markers, maternal age, gestational age, and ultrasound findings help determine the likelihood of these chromosomal conditions in the fetus. In addition to the traditional triple marker analysis, including a graphical representation enhances the interpretability of results.
No special preparation is required before undergoing the Triple Marker with Graph, 2nd Trimester test; you can eat or drink as per your daily routine. However, a pregnant woman must provide informed consent before undertaking this test. The laboratory personnel will explain the purpose, benefits, and limitations of this test.
What does Triple Marker with Graph, 2nd Trimester measure?
Contains 3 testsThe Triple Marker with Graph, 2nd Trimester test measures the levels of three specific markers in the blood of a pregnant woman. These markers are Alpha-Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), and Unconjugated Estriol (uE3)
The analysis of these three markers, along with other factors like maternal age and gestational age, helps assess the risk of Down syndrome, Edwards syndrome, and neural tube defects in the developing baby. The graph in the Triple Marker with Graph, 2nd Trimester test provides a visual representation of the levels of these markers during pregnancy.
It is noteworthy that the Triple Marker with Graph, 2nd Trimester test is a screening test, and any abnormal results may prompt further diagnostic testing for confirmation. Pregnant women should discuss their results and implications with their doctor.
HCG Beta Total Quantitative, Maternal
An HCG Beta Total Quantitative, Maternal test measures the levels of human chorionic gonadotropin (hCG) hormone in the blood. hCG is released in the blood during pregnancy and can be detected as early as 10 days after conception. The levels of this hormone gradually rise every 2 to 3 days (or 48 to 72 hours) and peak around 8 to 11 weeks after conception. After reaching the peak, the hCG levels decrease and remain steady for the rest of the pregnancy.
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Unconjugated Estriol
The Unconjugated Estriol test is used to measure Unconjugated Estriol (uE3), a type of estrogen that is particularly significant during pregnancy. It is produced by both the fetus and the placenta. The levels of uE3 in the mother's blood can give insights into the baby's well-being and can be crucial for identifying certain risks and complications in pregnancy.
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Alpha Feto Protein, Maternal
An Alpha Feto Protein, Maternal test measures the amount of Alpha Fetoprotein in expectant mothers usually during the second trimester (14th and 22nd weeks). AFP is a protein produced by the fetus, primarily by the fetal liver and yolk sac, and it passes into the mother's blood. The test is typically performed to screen for certain fetal abnormalities, particularly neural tube defects (NTDs) such as spina bifida and anencephaly, as well as chromosomal abnormalities like Down syndrome (trisomy 21), Edwards syndrome (Trisomy 18), etc.
Detecting these abnormalities early in pregnancy allows for appropriate medical management and intervention.
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Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Triple Marker with Graph, 2nd Trimester in Kolkata
Frequently Asked Questions about Triple Marker with Graph, 2nd Trimester in Kolkata
Q. What is the Triple Marker with Graph, 2nd Trimester test, and why is it important?
Q. What tests are done in the triple marker test?
Q. When can I go for the triple marker test during my pregnancy?
Q. How is the triple marker test performed, and is it safe for the baby?
Q. Is the Triple Marker with Graph, 2nd Trimester test only advised for women of age 35 years or more?
Q. Does Tata 1mg Labs offer the Triple Marker with Graph, 2nd Trimester test in Kolkata near me?
Q. Is home sample collection facility available for the Triple Marker with Graph, 2nd Trimester test in Kolkata with Tata 1mg Labs?
Q. How can I schedule the Triple Marker with Graph, 2nd Trimester test with Tata 1mg Labs in Kolkata?
Q. What is the price of the Triple Marker with Graph, 2nd Trimester test at Tata 1mg Labs in Kolkata?
Q. What is the estimated turnaround time for the results of the {test-name} test in Kolkata?
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References
- Conde-Agudelo A, Kafury-Goeta AC. Triple-marker test as screening for Down syndrome: a meta-analysis. 1998. In: Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK67524/
- Genetic Alliance; District of Columbia Department of Health. Understanding Genetics: A District of Columbia Guide for Patients and Health Professionals. Washington (DC): Genetic Alliance; 2010 Feb 17. Appendix F, Maternal Serum Marker Screening. Available from: https://www.ncbi.nlm.nih.gov/books/NBK132135/
- Driscoll DA, Gross SJ; Professional Practice Guidelines Committee. Screening for fetal aneuploidy and neural tube defects. Genet Med. 2009 Nov;11(11):818-21. [Accessed 02 May 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111043/
- Greene ND, Copp AJ. Neural tube defects. Annu Rev Neurosci. 2014;37:221-42. [Accessed 02 May 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486472/#:~:text=Neural%20tube%20defects%20(NTDs)%2C,both%20genetic%20and%20environmental%20factors.
- Screening for Down's syndrome, Edwards' syndrome and Patau's syndrome [Internet]. NHS; 19 April 2021 [Accessed 02 May 2024]. Available from: https://www.nhs.uk/pregnancy/your-pregnancy-care/screening-for-downs-edwards-pataus-syndrome/#:~:text=Combined%20test-,A%20screening%20test%20for%20Down's%20syndrome%2C%20Edwards'%20syndrome%20and%20Patau's,as%20the%2012%2Dweek%20scan.
- Sablok A, Sharma A, Ahmed CS, Kaul A. Performance of second-trimester maternal biochemistry screening (quadruple test vs. triple test) for trisomy 21: An Indian experience. Indian J Med Res. 2021 May;154(5):716-722. [Accessed 02 May 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210531/
- Gordon S, Umandap C, Langaker MD. Prenatal Genetic Screening. [Updated 2023 Jan 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557702/
- Commit to Healthy Choices to Help Prevent Birth Defects [Internet]. CDC; 28 June 2023 [Accessed 02 May 2024]. Available from: https://www.cdc.gov/ncbddd/birthdefects/prevention.html
- Institute of Medicine (US) Committee on Improving Birth Outcomes; Bale JR, Stoll BJ, Lucas AO, editors. Reducing Birth Defects: Meeting the Challenge in the Developing World. Washington (DC): National Academies Press (US); 2003. 3, Interventions to Reduce the Impact of Birth Defects. [Accessed 02 May 2024]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK222083/
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