Typhidot, IgG & IgM
Understanding Typhidot, IgG & IgM
What is Typhidot, IgG & IgM?
A Typhidot, IgG & IgM test is done to detect the presence or absence of antibodies (IgG and IgM) against Salmonella typhi, the bacteria that causes typhoid fever. This is a rapid, easy-to-perform, user-friendly, accurate, and reliable test to identify a typhoid infection. Testing is important as some infected individuals may not exhibit any symptoms yet can spread the infection to others.
Typhoid fever, or enteric fever, is a bacterial infection that can spread throughout the body, affecting many organs. It is common in places with poor sanitation, lack of safe drinking water, food prepared in unhygienic conditions, and poor hygiene. Thus, access to safe/clean water, adequate sanitation, and hygiene among food handlers and typhoid vaccinators effectively prevent typhoid fever.
Typhoid manifests as fever, loss of appetite, stomach pain, diarrhea, and skin rash. You can get tested with a Typhidot, IgG & IgM test if you experience symptoms suggestive of typhoid, have been in contact with a typhoid patient, or have traveled to an area where typhoid is prevalent. Typhoid fever is a potentially serious and life-threatening infection if left untreated.
Rapid detection and appropriate treatment administration are essential to prevent typhoid outbreaks and severe complications, such as intestinal bleeding or perforation, hepatitis, shock, or pneumonia. Without prompt treatment, typhoid can be fatal. Since a Typhidot, IgG & IgM test does not require any special laboratory setting or equipment and provides specific, reliable, and easy-to-interpret test results, it is an extremely valuable diagnostic tool.
Usually, no special preparation is required for this test; you may eat and drink as per your daily routine. However, several factors can affect the accuracy of typhoid IgG and IgM tests, including the timing of the test, the quality of the testing materials, and the presence of interfering substances in the blood. False-positive results on the typhoid IgG antibody test can also occur in people who have received the typhoid vaccine or have previously been exposed to other strains of the Salmonella bacteria.
Talk to your doctor about your specific test results. Narrate your complete medical history to help them correlate your clinical and laboratory findings and formulate your treatment plan.
What is Typhidot, IgG & IgM used for?
A Typhidot, IgG & IgM test is done:
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As part of the fever panel.
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In case of signs or symptoms of typhoid (enteric) fever, such as headache, high fever, abdominal pain, diarrhea, weight loss, or skin rashes.
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To screen people who are at a high risk of contracting typhoid fever, such as those who have just returned from a trip to a region where the illness is widespread or who have recently come in contact with infected people.
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To evaluate a patient’s response to typhoid fever treatment, and to determine treatment effectiveness.
What does Typhidot, IgG & IgM measure?
Contains 2 testsA Typhidot, IgG & IgM test is an important diagnostic tool to diagnose typhoid fever. This test usually shows the infection within 2-3 days and detects IgM and IgG antibodies, illustrating a recent and a past infection respectively. When Salmonella typhi, the causative bacteria from typhoid, enters the body, your immune system, as a response, releases two types of antibodies (specific proteins), IgM and IgG, against the outer membrane protein of Salmonella typhi.
Typhi Dot, IgM
The Typhi Dot, IgM test is an important and rapid diagnostic tool to diagnose typhoid fever. This test usually shows the typhoid infection within 2-3 days by detecting IgM antibodies, illustrating an active infection respectively. When Salmonella typhi enters the body, your immune system produces IgM antibodies as the body's first response of defense against the outer membrane protein of Salmonella typhi.
IgM antibodies are usually present in higher concentrations shortly after infection before gradually decreasing and eventually disappearing. Therefore, a positive IgM test for Salmonella Typhi typically suggests a recent or acute infection.
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Typhi Dot, IgG
The Typhi Dot, IgG test is performed to detect the presence or absence of IgG antibodies against Salmonella typhi, the bacteria that causes typhoid fever. IgG antibodies are the most frequent type of antibody, which are developed at a later stage, usually 2-3 weeks after the virus invades the body and causes the infection, and it remains in the body for life. Thus, IgG antibodies indicate if an individual has been infected with typhoid.
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