Combinib
Combinib Products are primarily used for
Breast cancer
About Combinib Products
Combinib Products side effects
Common
Side Effects of Combinib are Back pain, Cough, Diarrhea, Fatigue, Headache, Insomnia (difficulty in sleeping), Nausea, Rash, Stomatitis (Inflammation of the mouth), Vomiting, Weakness, Breathlessness, Decreased appetite, Dry skin, Hair loss, Itching, Nail disorder, Nosebleeds, Dyspepsia, Palmar-plantar erythrodysesthesia syndrome, Pain in extremity, Paronychia, Increased alanine aminotransferase, Increased aspartate aminotransferase.
Severe
Side Effects of Combinib are Interstitial lung disease, Liver toxicity, Decreased in left ventricular ejection fraction, Stevens-Johnson syndrome, Toxic epidermal necrolysis, Ventricular arrhythmia, Qt interval prolongation.
How Combinib Products work
Lapatinib is an anti-cancer medication. This works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways.
Patient Concerns about Combinib Products
Frequently asked questions about Combinib Products
Frequently asked questions about Lapatinib
Q. Is Combinib 250mg Tablet a chemotherapy medicine?
No, this is a targeted drug that belongs to a class of anti-cancer medicines. They are more specific than chemotherapy in their mechanisms of action. Combinib 250mg Tablet belongs to the tyrosine kinase inhibitors group of medicines. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.
Q. Can Combinib 250mg Tablet be given in combination with other anti-cancer drug?
Yes, Combinib 250mg Tablet can be used with other anti-cancer drugs. Generally, it is used in combination with capecitabine to treat advanced breast cancer in patients who have already been treated with chemotherapy. Combinib 250mg Tablet is also used with letrozole to treat breast cancer in post-menopausal women.
Q. How should I take Combinib 250mg Tablet?
You should take Combinib 250mg Tablet exactly as advised by your doctor. Swallow Combinib 250mg Tablet tablets whole with a glass of water, at the same time each day. You must take Combinib 250mg Tablet 1 hour before or 1 hour after meals and at the same time concerning food each day (e.g., you could always take your tablet one hour before breakfast).
Q. Does Combinib 250mg Tablet have any effect on liver?
Combinib 250mg Tablet may cause liver damage which can be severe or life-threatening. Liver damage can occur as soon as several days or as late as several months after the start of treatment with Combinib 250mg Tablet. Inform your doctor if you have or had liver disease. If you experience any of the symptoms such as itching, change in color of the skin or eyes (yellowing), discoloration of urine, pain in the upper right part of the stomach, unusual bleeding or bruising, or pale or dark stools, call your doctor immediately.
Q. How should I manage diarrhea while taking Combinib 250mg Tablet?
If you suffer from diarrhea while taking Combinib 250mg Tablet, you should drink plenty of fluids (8 to 10 glasses a day) such as water, sports drinks, or other clear liquids. You should eat low-fat, high protein foods instead of fatty or spicy foods. Eating cooked vegetables instead of raw vegetables and removing the skin from fruits before eating can also be helpful. Try to avoid milk and milk products (including ice cream) and herbal supplements (some may cause diarrhoea). Inform the doctor, if the condition persists, who may interrupt the treatment depending on the severity of diarrhea.
Q. How can I take care of my skin while on Combinib 250mg Tablet?
Your doctor will check your skin before and during the treatment. If you have sensitive skin, use a soap-free cleanser and beauty products that are fragrance-free and hypoallergenic. It is also advised that you use sunscreen with an SPF (Sun Protection Factor) of 30 or higher. Inform your doctor immediately if you get a rash.
Q. What tests will the doctor advise before starting Combinib 250mg Tablet?
You may need extra tests to check that your heart and liver are working properly. Combinib 250mg Tablet may change the way your heart beats and pumps blood through your body. Your doctor will monitor you carefully to see whether Combinib 250mg Tablet has affected your heart. Along with that, your doctor will get your liver function investigated. Based on the results of these tests, the doctor will decide whether dose adjustment or discontinuation of treatment is required.
Q. How long after Combinib 250mg Tablet can I plan pregnancy?
Use an effective method of contraception to avoid pregnancy while you are taking Combinib 250mg Tablet and continue for at least 1 week after the last dose. Inform your doctor if you become pregnant, who will decide whether to stop or continue treatment.