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People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.

Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

You can take Vildagliptin tablets before, with or after meals. If you have been prescribed to take this medicine once daily, then take it in the morning. In case you have to take it twice daily, then you should prefer taking the first dose in the morning and the second dose in the evening.

Yes, Vildagliptin may cause hypoglycemia (low blood sugar), but the chances are lesser as compared to other antidiabetic drugs. Evidence suggests that treatment with Vildagliptin has been shown to cause hypoglycemia in very rare cases. The risk is low even in those who are prone to hypoglycemia like elderly people or people being treated with insulin. However, the chance of hypoglycemia increases if Vildagliptin is taken along with other antidiabetic drugs.

No, Vildagliptin does not cause weight gain. Moreover, medicines, such as Vildagliptin, are generally supposed to decrease weight since they act by increasing satiety (feeling of fullness) and delaying emptying of the stomach. This further decreases hunger, restricting the patient from eating more than required.

No, Vildagliptin is not the same as Sitagliptin, but both drugs belong to the same class. Additionally, these two drugs have a similar mechanism of decreasing blood glucose levels.