Admesyl-400 Tablet

Written By Dr. Mayank, Pharm.D

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 28 Nov 2025 | 11:59 AM (IST)

Admesyl-400 Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

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General Information

Contains

S-Adenosyl L-Methoinine Disulfate Tosylate (400mg)

Marketer

Dr.Revmax Healthcare

Storage

Store below 30°C

The content is shown in English

Product introduction

Admesyl-400 Tablet may be taken with or without food. The dose will depend on the severity of your condition and your body weight. It is best swallowed whole, but you may need to break them to get the correct dose. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

Use of this medicine may cause some common side effects such as headache, dizziness, vomiting, upset stomach, diarrhea, constipation, and insomnia. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea and constipation.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.

Uses of Admesyl Tablet

Treatment of Liver disease

Benefits of Admesyl Tablet

Treatment of Liver disease
Liver problems can interfere with the body’s ability to remove toxins and digest food properly, leading to fatigue, poor digestion, and overall weakness. Admesyl-400 Tablet supports liver function, helps protect liver cells from damage, and improves their recovery. It aids in maintaining better liver health and reducing complications.

Side effects of Admesyl Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Admesyl

Headache
Dizziness
Vomiting
Upset stomach
Diarrhea
Constipation
Insomnia (difficulty in sleeping)

How to use Admesyl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Admesyl-400 Tablet may be taken with or without food.

How Admesyl Tablet works

Admesyl-400 Tablet contains S-Adenosyl L-Methoinine Disulfate Tosylate, also known as SAMe, a nutritional supplement, that can restore Glutathione concentrations in the liver and also improves liver damage. SAMe is also involved in many biochemical reactions in the human body that regulate the growth, death and differentiation of hepatocytes (liver cells). Because liver function is compromised in people suffering from liver disease, supplementation with Admesyl-400 Tablet is beneficial.

All substitutes for Admesyl-400 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Admesyl-400 Tablet is prescribed for the treatment of liver disease.
Seek immediate medical attention if you have difficulty breathing after taking the drug.
Admesyl-400 Tablet may interfere with surgery. Its use should be discontinued at least two weeks prior to surgery.
Avoid smoking and drinking as it further degrades liver functioning.
You will be regularly monitored for blood creatinine and blood/urine urea levels while on treatment with Admesyl-400 Tablet.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Admesyl-400 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Admesyl-400 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Admesyl-400 Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Admesyl-400 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Admesyl-400 Tablet in patients with kidney disease. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Admesyl-400 Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Frequently asked questions

What is Admesyl-400 Tablet used for?

Admesyl-400 Tablet is used to treat liver diseases where bile flow is reduced (intrahepatic cholestasis). It protects liver cells from harmful substances and helps the liver function normally.

How does taking Admesyl-400 Tablet help with joint pain?

Admesyl-400 Tablet is usually used to support liver health, but due to its anti‑inflammatory properties, it can also help reduce pain and improve joint function, similar to common arthritis medicines but with fewer side effects. Your doctor will evaluate the need for this medicine and advise on the dose and duration for the best results.

Can Admesyl-400 Tablet improve symptoms of depression?

Admesyl-400 Tablet is usually used to support liver health. However, some people find that it helps improve mood and reduce depression symptoms. Always use this medicine only as prescribed by your doctor.

Is Admesyl-400 Tablet natural or synthetic?

Admesyl-400 Tablet contains SAMe, which is a natural compound made by the body but can also be taken as a synthetic supplement to increase low levels.

Can Admesyl-400 Tablet help liver problems?

Admesyl-400 Tablet can support liver function and help protect liver cells. Your doctor will prescribe the dose and duration of this medicine for the best results.

Fact Box

Chemical Class

Sulfonium compounds

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents

Related lab tests

Bilirubin Direct

Bilirubin Indirect

Bilirubin Total

Liver Function Test

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: Stafford Laboratories Pvt. Ltd
Address: 143, Raipur Ind. Area, Bhagwanpur, Roorkee, UK

Marketer details

Name: Dr.Revmax Healthcare
Address: 2nd floor , Plot No: 81/3 ,Door No: 02-07/1/81 B , INCOIS Road , PragathinagarKukatpally , Hyderabad-500090,Medchal I Malkajgiri Dist.,Telangana , INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Admesyl-400 Tablet

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Admesyl Tablet

Benefits of Admesyl Tablet

Side effects of Admesyl Tablet

How to use Admesyl Tablet

How Admesyl Tablet works

All substitutes for Admesyl-400 Tablet

Alsame Tablet

Mednosam 400 Tablet

ADEBEST 400mg Tablet

Samorac 400 Tablet

Sambrace 400 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Admesyl-400 Tablet used for?

How does taking Admesyl-400 Tablet help with joint pain?

Can Admesyl-400 Tablet improve symptoms of depression?

Is Admesyl-400 Tablet natural or synthetic?

Can Admesyl-400 Tablet help liver problems?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Bilirubin Direct

Bilirubin Indirect

Bilirubin Total

Liver Function Test

References

Want to know more

Have issue with the content

Disclaimer

Manufacturer details

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests