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Acivir 400mg Syrup

Acyclovir (400mg)
Genuine
Authenticity Assured
Prescription
required
NPPA Regulated
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Acivir 400mg Syrup is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 May 2026 | 05:59 PM (IST)
₹84.5 MRP ₹93.7510% off 
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General Information

Contains

Acyclovir (400mg)

Marketer

Cipla Ltd
The content is shown in English
Acivir 400mg Syrup image
Acivir 400mg Syrup image

Product introduction

Acivir 400mg Syrup should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Dissolve it in a glass of water before taking it. It may be taken with or without food, but it is better to take it at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine, as it helps to prevent dehydration and kidney damage.

Some side effects of this medicine include headache, dizziness, vomiting, nausea, fatigue, and fever. Inform your doctor if these side effects do not resolve or persist for a longer duration. 


Acivir 400mg Syrup should be used with caution in people with kidney problems, dehydration, or weakened immune systems. It is contraindicated in those allergic to this medicine or similar medicines. Drink plenty of water during treatment to protect kidney function. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Acivir Syrup

Benefits of Acivir Syrup

Genital herpes infection
Genital herpes is a viral infection that causes painful blisters or sores in the genital area. Acivir 400mg Syrup helps reduce the severity and duration of these outbreaks by controlling the growth of the virus. It also helps relieve pain, itching, and discomfort while promoting faster healing.
Chickenpox
Chickenpox causes itchy blisters, fever, and tiredness, mainly in children. Acivir 400mg Syrup helps control the spread of the virus, reduces the number of blisters, and speeds up recovery. It also lowers the risk of complications, helping the child feel better sooner.
Herpes Simplex Virus Infections
Herpes simplex infections can cause cold sores, blisters, or painful skin lesions. Acivir 400mg Syrup works by stopping the virus from multiplying, helping reduce symptoms like pain and itching. It also shortens healing time and prevents new sores from forming.
Herpes labialis
Herpes labialis, commonly known as cold sores, causes painful blisters around the lips and mouth. Acivir 400mg Syrup helps stop the virus from multiplying, which reduces pain, burning, and itching. It also speeds up healing and helps prevent the formation of new sores.
Shingles
Shingles is a viral infection that causes a painful rash. Acivir 400mg Syrup can shorten the length and severity of shingles. It is most effective if you start taking it as soon as possible after the rash appears. Keeping the immune system healthy is the best way to prevent shingles. Maintaining good hygiene is another way of preventing shingles.

Side effects of Acivir Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acivir
  • Vomiting
  • Rash
  • Nausea
  • Dry skin
  • Burning sensation
  • General discomfort
  • Itching
  • Urticaria
  • Inflammation of vein
  • Dry lips
  • Skin peeling

How to use Acivir Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Acivir 400mg Syrup may be taken with or without food.

How Acivir Syrup works

Acivir 400mg Syrup is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Quick tips

  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage.
  • If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Acivir 400mg Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Acivir 400mg Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Acivir 400mg Syrup should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Acivir 400mg Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Acivir 400mg Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
It is advisable to drink plenty of water while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Acivir 400mg Syrup in patients with liver disease.

Interaction with drugs

Taking Acivir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tenofovir disoproxil fumarate (Oral Route)

Do not consume Tenofovir disoproxil fumarate with Acyclovir. If concurrent use is essential, your doctor may monitor your kidney function closely.
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Ciclosporin (Oral Route)

Caution is advised when taking Ciclosporin with Acyclovir. Your doctor may closely monitor the effects of Acyclovir if used concurrently with Ciclosporin and adjust the dose if needed. Acyclovir may raise blood levels of Ciclosporin.
Severe

Ciclosporin (Injection Route)

Caution is advised when taking Ciclosporin with Acyclovir. Your doctor may closely monitor the effects of Acyclovir if used concurrently with Ciclosporin and adjust the dose if needed. Acyclovir may raise blood levels of Ciclosporin.
Moderate

Ceftriaxone (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your kidney function.

Frequently asked questions

Acivir 400mg Syrup is an antiviral medicine effective against herpes simplex and varicella zoster viruses. It does not cure infections caused by these viruses but helps to minimize the symptoms and shorten the duration of infection. It does not remove the viruses from the body but prevents the viruses from dividing and spreading.
No, you can infect other people, even while you are being treated with Acivir 400mg Syrup. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.
Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.
Older adults (over age 65 years) tend to experience more side effects when taking Acivir 400mg Syrup. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Acivir 400mg Syrup, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.
Accidental, repeated overdoses of oral Acivir 400mg Syrup over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.
Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Acivir 400mg Syrup. If you are not responding to Acivir 400mg Syrup, the possibility of drug resistance should be checked.
Hair loss is an uncommon side effect of Acivir 400mg Syrup. It stops when the medicine is discontinued.
Acivir 400mg Syrup is an antiviral medicine effective against herpes simplex and varicella zoster viruses. It does not cure infections caused by these viruses but helps to minimize the symptoms and shorten the duration of infection. It does not remove the viruses from the body but prevents the viruses from dividing and spreading.
No, you can infect other people, even while you are being treated with Acivir 400mg Syrup. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.
Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.
Older adults (over age 65 years) tend to experience more side effects when taking Acivir 400mg Syrup. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Acivir 400mg Syrup, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.
Accidental, repeated overdoses of oral Acivir 400mg Syrup over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.
Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Acivir 400mg Syrup. If you are not responding to Acivir 400mg Syrup, the possibility of drug resistance should be checked.
Hair loss is an uncommon side effect of Acivir 400mg Syrup. It stops when the medicine is discontinued.

Fact Box

Chemical Class

Hypoxanthines

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral Agents (Non-HIV)

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Varicella Zoster IgG

Varicella Zoster IgM

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1594-1600.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 846-47.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 18-22.
  4. Aciclovir. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2007 [revised 15 Aug. 2018]. [Accessed 29 Jan. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
  6. Acyclovir [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2005. [Accessed 25 Jul. 2024] (online) Available from:
  7. Acyclovir [Prescribing Information]. München, Germany: DENK PHARMA GmbH & Co. KG; 2019. [Accessed 21 Oct. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

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