Actemra 400mg INJECTION

Tocilizumab (400mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Actemra 400mg INJECTION is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces swelling in these conditions by blocking TNF alpha.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 11 Apr 2026 | 05:23 PM (IST)

₹37257

₹40545

8% off

Get for

₹36257

on orders above ₹1200

Use Code 1MGNEWPLUS

Get for

₹36257

on orders above ₹300

Use Code 1MGNEW

1/2

Welcome Gift | For First Order

15% EXTRA OFF

1 Injection

Gurgaon

Save more with additional offers

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Tocilizumab (400mg)

Marketer

Roche Products India Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Actemra 400mg INJECTION is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better.

The most common side effects seen with this medicine include headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, and nasopharyngitis (pain or irritation in the throat). Consult your doctor if any of the side effects persist or bother you. Your doctor may be able to help with ways to reduce or prevent these symptoms. You may also be more prone to infections when you are being treated with this medicine. Tell your doctor right away if you develop any symptoms of an infection like fever, cough, rash, loose stools, or flu-like symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. While on treatment with this medicine, your doctor may monitor your blood counts by taking regular blood tests to make sure the medicine is not affecting your blood counts. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine.

Uses of Actemra Injection

Benefits of Actemra Injection

Treatment of Ulcerative colitis
Ulcerative colitis is a condition that causes redness and swelling in the large intestine and the rectum (lower part of large intestine). This can cause bleeding, frequent passing of stool and stomach pain. Actemra 400mg INJECTION reduces the pain and swelling and gives you relief from these symptoms. It reduces the discomfort and helps you live your life normally.
Actemra 400mg INJECTION if taken as prescribed can prevent the return of ulcerative colitis flare (return or worsening of your symptoms). Drink plenty of fluids while taking it to make sure you stay hydrated.

Treatment of Psoriasis
Psoriasis is a condition where the cells in the body grow too quickly and form scales and dry, itchy patches. They can grow anywhere, but most appear on the elbows, knees, scalp, and lower back. Actemra 400mg INJECTION reduces the scaly, itchy patches which may develop on different parts of the body. It also reduces dryness associated with Psoriasis and improves skin condition. This helps boost your self-confidence and improves quality of your life. It may take several months to become fully effective. Use it exactly and for as long as it is prescribed to get the most benefit.

Treatment of Rheumatoid arthritis
Rheumatoid arthritis or RA is an autoimmune disorder, in which the immune system starts attacking the lining of your joints. This causes pain and swelling in the joints.

Actemra 400mg INJECTION helps treat rheumatoid arthritis. It makes the immune system function normally and prevents it from attacking the body. This gives relief from the symptoms such as pain, swelling, and stiffness in the joints. This helps in easy movement and makes you do your daily activities more easily.

You may notice some relief of joint swelling, pain, and stiffness within the first 8 weeks of treatment with Actemra 400mg INJECTION.

Side effects of Actemra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actemra

Headache
High blood pressure
Upper respiratory tract infection
Injection site reactions (pain, swelling, redness)

How to use Actemra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Actemra Injection works

Actemra 400mg INJECTION blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

Quick tips

Actemra 400mg INJECTION is given as a drip (intravenous infusion) or as an injection directly into a vein.
You may be asked for regular blood tests to check blood counts, cholesterol level and liver functioning during the treatment.
It might make you feel dizzy. If this happens, avoid driving or operating on machinery.
It makes it hard to fight with an infection. Inform your doctor if you notice fever, cough or stomach pain.
Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
Do not stop taking medicine without talking to your doctor first.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actemra 400mg INJECTION. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Actemra 400mg INJECTION during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Actemra 400mg INJECTION during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Actemra 400mg INJECTION alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Actemra 400mg INJECTION should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Limited information is available on the use of Actemra 400mg INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.

Liver

CAUTION

Actemra 400mg INJECTION should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Actemra 400mg INJECTION is not recommended in patients with active liver disease.

Interaction with drugs

Taking Actemra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Tocilizumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Life-threatening

Adalimumab (Injection Route)

Do not consume Tocilizumab with Adalimumab.

Life-threatening

Etanercept (Injection Route)

Do not consume Tocilizumab with Etanercept.

Life-threatening

Golimumab (Injection Route)

Do not consume Tocilizumab with Golimumab.

Life-threatening

Infliximab (Injection Route)

Do not consume Tocilizumab with Infliximab.

Frequently asked questions

Who should be treated with Actemra 400mg INJECTION?

Actemra 400mg INJECTION should be given for treating patients suffering from moderate to severe Covid-19 infection who have persistent reduction in their oxygen levels (a condition called hypoxia) that continues to get worse. The hypoxia may continue to get worsened even after 24 to 48 hours of treatment with corticosteroids and supportive care.

Is Actemra 400mg INJECTION recommended for all Covid-19 patients? If not, why?

No, Actemra 400mg INJECTION is not recommended for all Covid-19 patients. This is because Actemra 400mg INJECTION has its own potential health hazards. Actemra 400mg INJECTION can lead to persistent serious infection and prolonged multiplication and shedding of the virus causing infection, so, it must be given only if the benefits outweigh the risks involved.

What are the side effects of Actemra 400mg INJECTION?

The potential side effects of Actemra 400mg INJECTION include anaphylaxis (serious allergic reaction) with infusion, transaminitis (very high levels of liver enzymes due to which they start moving into the bloodstream), leukopenia (a condition where a person has reduced white blood cells and hence increased risk for infections) and neutropenia (a condition where a person has abnormally low number of cells called neutrophils, that fight infections in our body). Some other side effects are risk of serious bacterial infections, viral infections and reactivation of tuberculosis (TB) virus.

Who should not be given Actemra 400mg INJECTION?

Actemra 400mg INJECTION should not be given to patients who have or ever had abnormal levels of liver enzymes (transaminitis), platelet counts (<50000), or if they have TB, or any active bacterial or viral infection. The use of Actemra 400mg INJECTION is contraindicated in pregnancy and breastfeeding mothers too, owing to its risk of developing serious complications.

What to do if there is no improvement seen after giving Actemra 400mg INJECTION too?

Your doctor will decide the next course of action if there is no improvement seen even after giving Actemra 400mg INJECTION. Actemra 400mg INJECTION will prevent inflammation of the lungs but will not cure the damage already done due to the existing disease. Recovery of the lungs takes time to improve. Persistent breathlessness after Actemra 400mg INJECTION administration requires further evaluation of patients for other lung-related issues (pulmonary intravascular coagulopathy) or heart-related problems (cardiac dysfunctions). Any other bacterial infections that might have occurred should also be treated separately.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

HLA - B27, PCR

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Tocilizumab. South San Francisco, California: Genentech, Inc. [Accessed 30 Jan. 2019] (online) Available from:

User feedback

What are you using Actemra Injection for?

Others

51%

Rheumatoid arthritis

36%

Crohn’s disease

Ankylosing spondylitis

Ulcerative colitis

How much was the improvement?

Average

37%

Poor

35%

Excellent

27%

What were the side-effects while using Actemra 400mg INJECTION?

No Side Effect

45%

Nasopharyngitis (inflammation of the throat and nasal passages)

18%

Upper respiratory tract infection

18%

Headache

High blood pressure

How do you take Actemra Injection?

With food

44%

With or without food

33%

Empty stomach

22%

Please rate Actemra 400mg INJECTION on price

Expensive

81%

Average

19%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Actemra 400mg INJECTION. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Actemra 400mg INJECTION

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Actemra Injection

Benefits of Actemra Injection

Side effects of Actemra Injection

How to use Actemra Injection

How Actemra Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Adalimumab (Injection Route)

Etanercept (Injection Route)

Golimumab (Injection Route)

Infliximab (Injection Route)

Frequently asked questions

Who should be treated with Actemra 400mg INJECTION?

Is Actemra 400mg INJECTION recommended for all Covid-19 patients? If not, why?

What are the side effects of Actemra 400mg INJECTION?

Who should not be given Actemra 400mg INJECTION?

What to do if there is no improvement seen after giving Actemra 400mg INJECTION too?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

HLA - B27, PCR

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

User feedback

What are you using Actemra Injection for?

How much was the improvement?

What were the side-effects while using Actemra 400mg INJECTION?

How do you take Actemra Injection?

Please rate Actemra 400mg INJECTION on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests