Calmac 50 Tablet
Prescription Required
Product introduction
Calmac 50 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.
Calmac 50 Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Anemia (low number of red blood cells) is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects which require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.
Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
Uses of Calmac Tablet
Side effects of Calmac Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Calmac
- Anemia (low number of red blood cells)
- Rash
- Abdominal pain
- Constipation
- Decreased appetite
- Dizziness
- Hot flashes
- Nausea
- Weakness
- Nocturia (increased urge to urinate during the night)
- Edema (swelling)
How to use Calmac Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calmac 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Calmac Tablet works
Calmac 50 Tablet blocks the effect of the natural male hormones on the growth of prostate cells. Calmac 50 Tablet also blocks the undesired effects of androgens in females such as excessive hair growth and acne.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Calmac 50 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Calmac 50 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Calmac 50 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Calmac 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Calmac 50 Tablet is safe to use in patients with kidney disease. No dose adjustment of Calmac 50 Tablet is recommended.
Liver
CAUTION
Calmac 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Calmac 50 Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable while you are taking this medicine.
Regular monitoring of liver function tests is advisable while you are taking this medicine.
What if you forget to take Calmac Tablet?
If you miss a dose of Calmac 50 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Calmac 50 Tablet
₹47.5/Tablet
Bical 50 Tablet
Intas Pharmaceuticals Ltd
₹32.1/tablet
32% cheaper
Calutide 50 Tablet
Cipla Ltd
₹48.5/tablet
2% costlier
Caluran 50 CP Tablet
Sun Pharmaceutical Industries Ltd
₹46.23/tablet
3% cheaper
Tabi Tablet
Dr Reddy's Laboratories Ltd
₹45.67/tablet
4% cheaper
Utamide Tablet
Intas Pharmaceuticals Ltd
₹48.5/tablet
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Quick tips
- You have been prescribed Calmac 50 Tablet for the treatment of prostate cancer.
- Take it with or without food, preferably at the same time every day.
- It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
- If you are diabetic, monitor your blood glucose regularly while taking Calmac 50 Tablet.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Do not stop taking the medication without talking to your doctor first.
Fact Box
Chemical Class
Trifluoromethylbenzenes Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Androgen Receptor Antagonists
Interaction with drugs
Taking Calmac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Bicalutamide with Domperidone.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Bicalutamide with Domperidone.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Bicalutamide with Domperidone.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Bicalutamide with Domperidone.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Bicalutamide with Domperidone.
Patient concerns
FAQs
Can Calmac 50 Tablet cause infertility?
There is limited data to support that Calmac 50 Tablet causes infertility. Calmac 50 Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).
What should I avoid while taking Calmac 50 Tablet?
Skin sensitivity has been observed in some patients while taking Calmac 50 Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Calmac 50 Tablet.
Is Calmac 50 Tablet a form of chemotherapy?
No, Calmac 50 Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Calmac 50 Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.
Does Calmac 50 Tablet cause hair loss?
Yes, Calmac 50 Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.
What is Calmac 50 Tablet prescribed for?
Calmac 50 Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Calmac 50 Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.
When should I take Calmac 50 Tablet?
Calmac 50 Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.
Can Calmac 50 Tablet cause diarrhea?
Yes, Calmac 50 Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.
How long do I need to take Calmac 50 Tablet?
Calmac 50 Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1766.
- Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
- Bicalutamide. Sellersville, PA: TEVA Pharmaceutical; 1995 [revised Jun. 2009]. [Accessed 26 Mar. 2019] (online) Available from:
- Bicalutamide. Capability Green: AstraZeneca UK; 2000 [revised 08 Feb. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- Bicalutamide [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2017. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.
Country of origin: India
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₹475
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MRP₹484 2% OFF
10.0 tablets in 1 strip
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