Cyramza 500mg Injection

Ramucirumab (500mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Cyramza 500mg Injection is an anticancer medication. It is used in the treatment of non-small cell lung cancer, stomach cancer and cancer of colon and rectum.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)

₹219924 MRP ₹2414369% off

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General Information

Contains

Ramucirumab (500mg)

Marketer

Eli Lilly and Company India Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

It is given as IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

High blood pressure is a very common side effect of this medicine. Hence, your doctor will monitor your blood pressure regularly while taking this medicine. You should remain hydrated as it may also cause diarrhea and headache as its side effects. It is known to reduce the red blood cells in your blood. Hence, regular blood tests are required to monitor your blood cells during treatment with this medicine.

Uses of Cyramza Injection

Benefits of Cyramza Injection

Stomach cancer
Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Cyramza 500mg Injection helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Cyramza 500mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Cyramza 500mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Cyramza Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cyramza

High blood pressure
Diarrhea
Headache
Decreased sodium level in blood
Anemia (low number of red blood cells)

How to use Cyramza Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cyramza Injection works

Cyramza 500mg Injection is an anticancer medication. It works by blocking the ‘VEGF receptor 2’ thereby cutting off the blood supply to the cancer cells. This slows the growth of cancer cells and eventually kills them.

Quick tips

Cyramza 500mg Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
Cyramza 500mg Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Cyramza 500mg Injection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cyramza 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Cyramza 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Cyramza 500mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Cyramza 500mg Injection does not usually affect your ability to drive.

Kidney

CAUTION

Cyramza 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Cyramza 500mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Cyramza with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Cholera Vaccine (Inactivated) (Oral Route)

Please consult with your doctor regarding required precautions.

Moderate

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Please consult with your doctor regarding required precautions.

Moderate

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Please consult with your doctor regarding required precautions.

Frequently asked questions

What is Cyramza 500mg Injection used for?

Cyramza 500mg Injection is a targeted cancer medicine used to treat several advanced cancers, such as stomach cancer (gastric or gastroesophageal junction), non-small cell lung cancer (NSCLC), colorectal cancer, and liver cancer (hepatocellular carcinoma). It works by blocking the formation of new blood vessels that feed blood to the cancer cells and is often used with chemotherapy.

How is Cyramza 500mg Injection given?

Cyramza 500mg Injection is given through an IV (intravenous) line in your arm. Each treatment usually takes about 60 minutes. You will receive it at a hospital or cancer treatment center. Your doctor will decide how often you need treatment, typically every 2-3 weeks, based on your specific condition.

What are the serious side effects of Cyramza 500mg Injection?

The serious side effects of Cyramza 500mg Injection include severe bleeding, gastrointestinal perforation, arterial blood clots or stroke, high blood pressure, kidney problems (protein in urine), liver problems in liver cancer patients, etc. Your doctor will monitor you closely for these complications.

Who should not take Cyramza 500mg Injection?

Individuals should not take Cyramza 500mg Injection if they are allergic to ramucirumab, have tumor involvement in major blood vessels, are actively bleeding, or have uncontrolled high blood pressure. It should be used with caution in people with liver cirrhosis or severe wound healing issues.

Can Cyramza 500mg Injection affect the brain or nervous system?

In rare cases, Cyramza 500mg Injection can cause a condition called posterior reversible encephalopathy syndrome (PRES). Symptoms may include headache, seizures, vision problems, or confusion. If this happens, treatment should be stopped immediately.

Can Cyramza 500mg Injection cause heart problems?

Cyramza 500mg Injection may raise the risk of heart failure or arterial blood clots, especially when used with other chemotherapy drugs. Tell your doctor if you have chest pain, shortness of breath, or swelling.

What are the signs of an allergic reaction to Cyramza 500mg Injection?

You should watch for signs of allergic reactions during or after Cyramza 500mg Injection treatment that include chills or shaking, fever, rash or hives, difficulty breathing, chest tightness, etc. Tell your healthcare team immediately if you experience any of these symptoms.

Can I continue my regular activities during Cyramza 500mg Injection treatment?

Most people can continue with their regular activities, but they should get plenty of rest, avoid crowds and sick people due to infection risk, and take special care to prevent cuts and injuries. If you are not sure of resuming your daily activities, check with your doctor about exercise and other activities.

How do I know if Cyramza 500mg Injection is working?

Your doctor will order regular scans to check tumor size, monitor your symptoms, perform physical exams, and track any improvement in your condition. It may take several weeks before changes can be seen.

How long do I need to stay on Cyramza 500mg Injection?

The Cyramza 500mg Injection treatment continues until your cancer worsens or you develop unacceptable side effects. Your doctor will assess your response regularly.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Vascular Endothelial Growth Factor (VEGF) Inhibitors

Related lab tests

Carcino Embryonic Antigen

References

User feedback

What are you using Cyramza Injection for?

Stomach cancer

100%

How much was the improvement?

Poor

50%

Average

33%

Excellent

17%

What were the side-effects while using Cyramza 500mg Injection?

High blood pressure

50%

No Side Effect

50%

How do you take Cyramza Injection?

With or without food

100%

Please rate Cyramza 500mg Injection on price

Expensive

83%

Average

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eli Lilly and Company India Pvt Ltd
Address: Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA

Vendor Details

Country of origin: United states

Lab tests offered by us

Why we need a prescription?

Cyramza 500mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cyramza Injection

Benefits of Cyramza Injection

Side effects of Cyramza Injection

How to use Cyramza Injection

How Cyramza Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Frequently asked questions

What is Cyramza 500mg Injection used for?

How is Cyramza 500mg Injection given?

What are the serious side effects of Cyramza 500mg Injection?

Who should not take Cyramza 500mg Injection?

Can Cyramza 500mg Injection affect the brain or nervous system?

Can Cyramza 500mg Injection cause heart problems?

What are the signs of an allergic reaction to Cyramza 500mg Injection?

Can I continue my regular activities during Cyramza 500mg Injection treatment?

How do I know if Cyramza 500mg Injection is working?

How long do I need to stay on Cyramza 500mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

References

User feedback

What are you using Cyramza Injection for?

How much was the improvement?

What were the side-effects while using Cyramza 500mg Injection?

How do you take Cyramza Injection?

Please rate Cyramza 500mg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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