D Void Nasal Spray

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 26 Jan 2026 | 10:32 PM (IST)

D Void Nasal Spray is used in the treatment of diabetes insipidus and bed-wetting. This medicine helps decrease the urge to urinate and help resume more normal life-style. It is generally used in patients who cannot take the oral form of medicine.

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Stored between 2-8°C

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General Information

Contains

Desmopressin (0.01%)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

D Void Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril.

The most common side effects of this medicine include nasal discomfort, nasopharyngitis, nasal congestion, sneezing, headache, nausea, and cough. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

It is generally a safe medicine but, before taking it, talk to your doctor about any health problems you have such as heart problems or high blood pressure (hypertension) or overactive thyroid gland or glaucoma or prostate enlargement. Let your doctor know about any other medicines you are taking to make sure you are safe. Ask your doctor for advice before using this medicine if you are pregnant or breastfeeding.

Uses of D Void Nasal Spray

Benefits of D Void Nasal Spray

Diabetes insipidus
Diabetes insipidus is a condition where the body produces large amounts of dilute urine, leading to excessive thirst and frequent urination. D Void Nasal Spray helps reduce urine output and control excessive thirst, supporting better fluid balance and improved daily comfort.

Bed-wetting
Bed wetting occurs when the body produces excess urine during sleep or bladder control is not fully developed. D Void Nasal Spray helps reduce nighttime urine production, which lowers the frequency of bed wetting episodes and supports better sleep quality and confidence.

Side effects of D Void Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of D Void

Nasal discomfort
Nasopharyngitis (inflammation of the throat and nasal passages)
Nasal congestion (stuffy nose)
Sneezing
Nosebleeds
Dizziness
Headache
Nausea
Cough

How to use D Void Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How D Void Nasal Spray works

D Void Nasal Spray is a synthetic form of vasopressin (natural hormone that balances water). It is rapidly absorbed into the bloodstream through the inner surface of the nose. Once absorbed, it works by causing reabsorption of water from the kidneys which controls excessive thirst and urination in diabetes insipidus. It also helps decrease night-time urine production in multiple sclerosis.

Quick tips

The right way to use the nasal spray:
- Shake the bottle before using the medicine.
- Clean your nose thoroughly before using the medicine.
- Insert the bottle tip into one nostril and close the other nostril.
- Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.
- Breathe out gently through your mouth and repeat the same process for the other nostril.
Limit the amount of fluids you drink with this medication.
Do not share the bottle with anyone else so that you do not spread germs.
Use the D Void Nasal Spray within 3 weeks of opening it and discard the rest.

Safety advice

Alcohol

No interaction found/established

Pregnancy

SAFE IF PRESCRIBED

D Void Nasal Spray is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking D Void with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Tolvaptan (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Aceclofenac (Oral Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.

Moderate

Aceclofenac (Injection Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.

Moderate

Aceclofenac (Oral Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.

Moderate

Amitriptyline (Oral Route)

Caution is advised when taking Desmopressin with Amitriptyline. Your doctor may monitor your sodium levels closely.

Frequently asked questions

What precautions do I need to take while on D Void Nasal Spray?

Follow all the instructions given by your doctor strictly. Restrict water intake after taking D Void Nasal Spray as drinking too much water can lead to fluid overload, which is a serious side effect. Try not to swallow water while swimming.

How long do I need to give D Void Nasal Spray to my child for bedwetting?

D Void Nasal Spray is usually prescribed for 3 months for bedwetting. After 3 months, your doctor will stop the medicine for a week to assess whether your child still needs D Void Nasal Spray or not.

Does D Void Nasal Spray cure bed wetting?

No, D Void Nasal Spray does not cure bedwetting, but it helps control bedwetting. It works by replacing a hormone (vasopressin) that is normally produced in the body to help balance the amount of water and salt.

Does D Void Nasal Spray make you gain weight?

No, D Void Nasal Spray itself does not cause weight gain. D Void Nasal Spray may cause fluid overload which may in turn cause weight gain. Fluid overload is a serious side effect and you should immediately contact your doctor if you experience headache, nausea, vomiting, restlessness, tiredness, loss of appetite, sleepiness, confusion and muscle cramps.

Is D Void Nasal Spray a diuretic?

No, D Void Nasal Spray is not a diuretic. It is a hormone which helps lower urine output in patients with diabetes insipidus and helps control bedwetting in children. It works by reducing the amount of urine produced by the kidneys, thereby reducing the frequency of urination.

Fact Box

Chemical Class

Synthetic vasopressin analoguesues

Habit Forming

Therapeutic Class

HORMONES

Action Class

Vasopressin Analogues

Related lab tests

Anti Diuretic Hormone

Osmolality - Serum

Osmolality - Urine

References

Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 712-14.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 375.
Medlineplus. Desmopressin Nasal. [Accessed 04 Apr. 2019] (online) Available from:
Desmopressin. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 2007. [Accessed 04 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 3 Apr. 2019] (online) Available from:
Desmopressin Acetate [Prescribing Information]. Mumbai, Maharashtra: Sun Pharmaceutical Industries Ltd.; 2012. [Accessed 17 Jun. 2023] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India

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D Void Nasal Spray

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General Information

Contains

Marketer

Storage

Product introduction

Uses of D Void Nasal Spray

Benefits of D Void Nasal Spray

Side effects of D Void Nasal Spray

How to use D Void Nasal Spray

How D Void Nasal Spray works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tolvaptan (Oral Route)

Aceclofenac (Oral Route)

Aceclofenac (Injection Route)

Aceclofenac (Oral Route)

Amitriptyline (Oral Route)

Frequently asked questions

What precautions do I need to take while on D Void Nasal Spray?

How long do I need to give D Void Nasal Spray to my child for bedwetting?

Does D Void Nasal Spray cure bed wetting?

Does D Void Nasal Spray make you gain weight?

Is D Void Nasal Spray a diuretic?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Diuretic Hormone

Osmolality - Serum

Osmolality - Urine

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests