Endobloc 10 Tablet
Prescription Required
Product introduction
Endobloc 10 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.
Endobloc 10 Tablet may be taken with or without food but, it is better to take it in a dose and duration as advised by the doctor. In case, you have missed any dose than it is better to take another one as soon as you remember it.
The most common side effects of this medicine are peripheral edema, nasal congestion, sinusitis, and flushing. Let your doctor know if any of these side effects bothers you or persists for a longer duration. Dizziness may also occur in some people, so do not drive or do anything that requires mental focus if you experience such symptom.
Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor’s advice.
Uses of Endobloc Tablet
Side effects of Endobloc Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endobloc
- Peripheral edema
- Nasal congestion (stuffy nose)
- Sinus inflammation
- Flushing (sense of warmth in the face, ears, neck and trunk)
How to use Endobloc Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endobloc 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Endobloc Tablet works
Endobloc 10 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Endobloc 10 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Endobloc 10 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Endobloc 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Endobloc 10 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Endobloc 10 Tablet may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
Kidney
CAUTION
Endobloc 10 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Endobloc 10 Tablet may be needed. Please consult your doctor.
Limited information is available on use of Endobloc 10 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Limited information is available on use of Endobloc 10 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Endobloc 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Endobloc 10 Tablet may be needed. Please consult your doctor.
What if you forget to take Endobloc Tablet?
If you miss a dose of Endobloc 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Endobloc 10 Tablet
₹295.7/Tablet
Pulmonext 10 Tablet
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Quick tips
- Your doctor has prescribed Endobloc 10 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
- It helps improve your quality of life, exercising ability, and delay disease progression.
- Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
- Do not drive or do anything requiring concentration until you know how Endobloc 10 Tablet affects you.
- Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
- Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Endobloc 10 Tablet as it is toxic to an unborn baby.
- Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
- Your doctor has prescribed Endobloc 10 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
- It helps improve your quality of life, exercising ability, and delay disease progression.
- Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
- Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
- Do not drive or do anything requiring concentration until you know how Endobloc 10 Tablet affects you.
- Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
- Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Fact Box
Chemical Class
Diphenylmethanes Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Endothelin Receptor Antagonists (ERAs)
Interaction with drugs
Taking Endobloc with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Rifampicin may raise blood levels of Ambrisentan.
Your doctor may monitor your treatment.
Rifampicin may raise blood levels of Ambrisentan.
Your doctor may monitor your treatment.
Ciclosporin may raise blood levels of Ambrisentan.
watch out for symptoms such as constipation, flushing or swelling under the skin and consult your doctor if you experience them.
Ciclosporin may raise blood levels of Ambrisentan.
watch out for symptoms such as constipation, flushing or swelling under the skin and consult your doctor if you experience them.
Ambrisentan may raise blood levels of Conjugated Estrogens.
Talk to your doctor if you notice any unusual symptoms.
Patient concerns
User feedback
Patients taking Endobloc 10 Tablet
Once A Day
100%
What are you using Endobloc Tablet for?
Pulmonary art*
100%
*Pulmonary arterial hypertension (PAH)
How much was the improvement?
Excellent
48%
Average
38%
Poor
14%
What were the side-effects while using Endobloc 10 Tablet?
No Side Effec*
33%
Runny nose
22%
Headache
22%
Dizziness
11%
Palpitations
11%
*No Side Effect
How do you take Endobloc Tablet?
With food
83%
With or witho*
17%
*With or without food
Please rate Endobloc 10 Tablet on price
Expensive
50%
Average
39%
Not Expensive
11%
FAQs
Can Endobloc 10 Tablet cause liver problems?
Yes, Endobloc 10 Tablet commonly causes an increase in liver enzymes. It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.
How should Endobloc 10 Tablet be taken?
Usually, the doctors advise to take one dose of Endobloc 10 Tablet. You can take it with or without food but prefer taking it at the same time each day. Swallow it whole with a glass of water. Do not crush, chew or break it into pieces.
Can I stop taking Endobloc 10 Tablet on my own?
No, you should not stop taking Endobloc 10 Tablet without consulting your doctor as this may worsen your condition. Talk to your doctor if you need to stop it.
What is the most important thing that I should know about Endobloc 10 Tablet?
Endobloc 10 Tablet may cause serious birth defects if taken during pregnancy. Therefore, every woman who is capable of becoming pregnant should get a pregnancy test done before starting Endobloc 10 Tablet. Additionally, during treatment with Endobloc 10 Tablet you should use two reliable methods of contraception to ensure that you do not get pregnant.
What are the serious side effects of Endobloc 10 Tablet?
The serious side effects of Endobloc 10 Tablet are swelling all over the body (fluid retention), decreased sperm count and low red blood cell count (anemia). Tell your doctor if you have any unusual weight gain, tiredness, or trouble breathing.
Why have I been prescribed Endobloc 10 Tablet?
Endobloc 10 Tablet is used to treat pulmonary hypertension in adults. Pulmonary hypertension is a condition wherein there is increased blood pressure in the pulmonary arteries (blood vessels that carry blood from heart to lungs). Endobloc 10 Tablet lowers the blood pressure by relaxing the pulmonary arteries, making it easier for the heart to pump blood through them.
What are the symptoms of overdose of Endobloc 10 Tablet?
Taking more than the recommended dose of Endobloc 10 Tablet may cause headache, flushing, dizziness, or nausea. It may cause low blood pressure which may further lead to lightheadedness. Contact your doctor immediately or seek emergency medical services in a nearby hospital if you take more than the recommended doses of this medicine.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 39-50.
- Name of medicine. Citywest Business Campus Dublin: GlaxoSmithKline (Ireland) Limited; 2008 [revised 31 Oct. 2018]. [Accessed 01 Apr. 2019] (online) Available from:
- Ambrisentan. Uxbridge, Middlesex: GlaxoSmithKline UK; 2008 [revised 31 Oct. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
- CiplaMed. Ambrisentan [Prescribing Information]. [Last reviewed: May 2018] [Accessed 09 Jun, 2023] (online) Available from:
- (ambrisentan) [Product Information]. [Accessed 09 Jun, 2023] (online) Available from:
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver Endobloc 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver Endobloc 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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