ES-Que 300mg Tablet SR is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It is also used to treat bipolar disorders.
ES-Que 300mg Tablet SR may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include decreased hemoglobin levels in the blood, increased triglycerides level in blood, decreased cholesterol level in blood, headache, extrapyramidal symptoms, dry mouth, and withdrawal symptoms. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.
You should be cautious while using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Mania means extremely excited or elevated mood. ES-Que 300mg Tablet SR helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking ES-Que 300mg Tablet SR will ensure that you have a better social life and are able to do daily activities more comfortably.
In Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. ES-Que 300mg Tablet SR helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Side effects of ES-Que Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of ES-Que
Weight gain
Constipation
Dizziness
Dryness in mouth
Fatigue
High blood pressure
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Sleepiness
Dyslipidemia
Increased appetite
How to use ES-Que Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ES-Que 300mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
How ES-Que Tablet SR works
ES-Que 300mg Tablet SR is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with ES-Que 300mg Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
ES-Que 300mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
ES-Que 300mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
ES-Que 300mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
ES-Que 300mg Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of ES-Que 300mg Tablet SR may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
ES-Que 300mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of ES-Que 300mg Tablet SR may be needed. Please consult your doctor.
What if you forget to take ES-Que Tablet SR?
If you miss a dose of ES-Que 300mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Concurrent use may cause serious disturbance in heart rhythm.
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Concurrent use may cause serious disturbance in heart rhythm.
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Concurrent use may cause serious disturbance in heart rhythm.
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ES-Que 300mg Tablet SR helps to correct chemical imbalances in the brain. It acts on various chemical messengers in the brain like dopamine and serotonin. It prevents the excessive activity of dopamine, helping to treat symptoms of schizophrenia and mania.
Is ES-Que 300mg Tablet SR a sleeping pill?
ES-Que 300mg Tablet SR can make you feel sleepy, but it is not used as a sleeping pill. ES-Que 300mg Tablet SR is approved for the treatment of symptoms of schizophrenia. It prevents as well as treats episodes of mania and depression in bipolar disorder. It is also used with other medicines to treat depression.
How long does ES-Que 300mg Tablet SR take to work?
You may start seeing an improvement within a week of starting ES-Que 300mg Tablet SR but full benefits may take about 4-6 weeks to appear.
Is ES-Que 300mg Tablet SR good for anxiety?
ES-Que 300mg Tablet SR has not been approved for the treatment of anxiety; however, your doctor may prescribe it for anxiety. Some studies suggest its use in post-traumatic stress disorder, generalized anxiety disorder, and anxiety associated with mood disorders.
What should I avoid while taking ES-Que 300mg Tablet SR?
ES-Que 300mg Tablet SR can cause drowsiness. So, do not drive, operate machinery or do anything dangerous until you know how ES-Que 300mg Tablet SR affects you. Do not drink alcohol while taking ES-Que 300mg Tablet SR as it may worsen the drowsiness. Avoid getting dehydrated or over-exposure to heat.
Can I stop taking ES-Que 300mg Tablet SR if I am better now?
No, you should not stop taking ES-Que 300mg Tablet SR without consulting your doctor. Suddenly stopping it may cause nausea, vomiting, headache, diarrhea, dizziness, irritability and inability to sleep. If you feel better, consult your doctor who will gradually reduce the dose before completely stopping it.
Can ES-Que 300mg Tablet SR cause weight gain?
Yes, weight gain is a common side effect of ES-Que 300mg Tablet SR. If you feel you are gaining weight, consult your doctor or a nutritionist who will suggest you a diet and some exercise to help you manage your weight.
How should ES-Que 300mg Tablet SR be taken?
Take ES-Que 300mg Tablet SR exactly as advised by your doctor. Do not split, chew or crush the tablets. Swallow the tablet whole with a glass of water. Do not take it with food. It is advised to take this medicine for at least one hour before a meal or at bedtime. Do not take grapefruit while taking ES-Que 300mg Tablet SR as it may affect the working of this medicine.
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References
Stahl SM, editor. Quetiapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 575-81.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1181-84.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Quetiapine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Quetiapine fumarate [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2013. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
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