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Mstarin Capsule

Midostaurin (25mg)
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Mstarin Capsule is a medicine used in the treatment of blood cancer (acute myeloid leukemia). It works by stopping the cancer cells from growing and multiplying. This way it stops the growth and spread of the cancer in the body and helps in disease management.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)
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28 soft gelatin capsules
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Product introduction

Mstarin Capsule is best taken with food. This will reduce the risk of nausea and vomiting. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, headache, musculoskeletal pain, nosebleed, hyperglycemia, and upper respiratory tract infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You have to avoid driving or attention seeking activity if you experience dizziness while taking this medicine.

Before taking it, tell your doctor if you have any other preexisting medical conditions or taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Mstarin Soft Gelatin Capsule

Benefits of Mstarin Soft Gelatin Capsule

Treatment of (Acute Myeloid Leukemia) Blood cancer
Mstarin Capsules helps treat a type of blood cancer called acute myeloid leukemia (AML). It stops certain enzymes from making the cancer cells grow and multiply. This medicine controls the cancer cell multiplication and improves disease management. It's often used with other treatments like chemotherapy. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Mstarin Soft Gelatin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mstarin
  • Febrile neutropenia
  • Nausea
  • Vomiting
  • Headache
  • Petechiae (red or purple spot caused by bleeding into the skin)
  • Musculoskeletal (bone, muscle or joint) pain
  • Nosebleeds
  • Infection
  • Increased glucose level in blood
  • Upper respiratory tract infection
  • Mucositis

How to use Mstarin Soft Gelatin Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mstarin Capsule should be taken with or after food.

How Mstarin Soft Gelatin Capsule works

Mstarin Capsule works by blocking the action of the abnormal protein that triggers the multiplication of cancer cells. This helps stop the spread of mast and cancer cells.

All substitutes for Mstarin Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take Mstarin Capsule exactly as your doctor tells you.
  • Your doctor may prescribe medicines to help prevent the nausea and vomiting during treatment with Mstarin Capsule.
  • Take Mstarin Capsule with food.
  • Do not take Mstarin Capsule for a condition for which it was not prescribed. Do not give Mstarin Capsule to other people, even if they have the same condition or symptoms you have. It may harm them.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mstarin Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Mstarin Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Mstarin Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Mstarin Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Mstarin Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Mstarin Capsule is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Mstarin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Lenvatinib (Oral Route)

Concurrent use should be avoided. Please consult with your doctor.
Severe

Carbamazepine (Oral Route)

Carbamazepine may increase the metabolism of Midostaurin.
Severe

Fosphenytoin (Injection Route)

Fosphenytoin may increase the metabolism of Midostaurin.
Severe

Phenobarbitone (Oral Route)

Do not consume Midostaurin with Phenobarbitone. Phenobarbitone may reduce blood levels of Midostaurin and its active form.
Severe

Phenobarbitone (Injection Route)

Do not consume Midostaurin with Phenobarbitone. Phenobarbitone may reduce blood levels of Midostaurin and its active form.

Fact Box

Chemical Class

Indolocarbazoles

Habit Forming

No

Action Class

Topical Bacterial Protein Synthesis Inhibitors
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: BDR Pharmaceuticals Internationals Pvt
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Mstarin Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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