Onivyde 43mg Infusion
Prescription Required
Product introduction
Onivyde 43mg Infusion is a chemotherapy drug used in combination with other medications to treat metastatic pancreatic cancer, particularly in patients whose cancer has progressed after other treatments. It attacks the cancer cells and prevents them from growing and spreading.
Onivyde 43mg Infusion is given as an intravenous (IV) infusion by a doctor or a nurse, generally in a hospital or a clinical setting. The dosing schedule is usually every two weeks, depending on your treatment plan. Make sure to attend all scheduled appointments to get the maximum benefit from the drug.
Common side effects of Onivyde 43mg Infusion include diarrhea, fatigue, vomiting, nausea, decreased appetite, and fever. Stay hydrated and get enough rest to reduce the side effects. If you experience severe side effects like intense abdominal pain, persistent vomiting, or severe diarrhea, contact your doctor immediately.
Onivyde 43mg Infusion can lower your immune system, so when on treatment with Onivyde 43mg Infusion, avoid crowded places and avoid contact with sick individuals and practice good hygiene. Do not receive live vaccines (such as those for measles, mumps, or chickenpox) while undergoing treatment. Onivyde 43mg Infusion can cause harm to an unborn baby, so it is important to avoid pregnancy during treatment and discuss contraceptive options with your doctor. Breastfeeding is also not recommended during treatment.
Uses of Onivyde Infusion
Benefits of Onivyde Infusion
In Treatment of Pancreatic cancer
Onivyde 43mg Infusion targets and kill cancer cells. This helps to slow the progression of metastatic pancreatic cancer, especially in patients whose cancer has progressed after other treatments. When combined with other chemotherapy drugs, Onivyde 43mg Infusion has been shown to improve survival rates and offer better disease control.
Side effects of Onivyde Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Onivyde
- Diarrhea
- Fatigue
- Vomiting
- Nausea
- Decreased appetite
- Stomatitis (Inflammation of the mouth)
- Fever
- Lymphopenia
- Decreased white blood cell count (neutrophils)
How to use Onivyde Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Onivyde Infusion works
Onivyde 43mg Infusion is a special form of a cancer-fighting drug called Irinotecan. Irinotecan works by blocking the ability of cancer cells to divide and grow, which eventually leads to their death. It does this by targeting an enzyme called topoisomerase I, which cancer cells need to replicate their DNA. In this formulation, Irinotecan is enclosed in tiny fat-like particles called liposomes and is pegylated, meaning it’s coated with a substance (PEG) that makes it stay in the bloodstream longer. This helps the drug stay active in the body for a longer period, giving it more time to reach the cancer cells. The liposomes also help target the drug more specifically to cancer cells, reducing the side effects on healthy cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Onivyde 43mg Infusion. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Onivyde 43mg Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Onivyde 43mg Infusion is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Onivyde 43mg Infusion may cause side effects which could affect your ability to drive.
During treatment patients should observe caution when driving or using machines.
During treatment patients should observe caution when driving or using machines.
Kidney
SAFE IF PRESCRIBED
Onivyde 43mg Infusion is safe to use in patients with kidney disease. No dose adjustment of Onivyde 43mg Infusion is recommended.
However, Onivyde 43mg Infusion is not recommended for use in patients with severe renal impairment.
However, Onivyde 43mg Infusion is not recommended for use in patients with severe renal impairment.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Onivyde 43mg Infusion in patients with liver disease. Please consult your doctor.
What if you forget to take Onivyde Infusion?
Since Onivyde 43mg Infusion is administered by a doctor or a nurse in a clinical setting, missed doses are uncommon. However, if a dose is missed, your doctor will reschedule the infusion based on your treatment plan. Be sure to attend all scheduled appointments.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Treatment with Onivyde 43mg Infusion can lead to dehydration, especially if you experience diarrhea or vomiting. Drink plenty of water and electrolytes throughout the day to keep your body hydrated.
- Onivyde 43mg Infusion is most effective when given on schedule. Make sure to attend all infusion appointments as directed by your doctor and inform them of any concerns or side effects between sessions.
- Onivyde 43mg Infusion can affect your white blood cells, making you more prone to infections. Regular blood tests will be necessary to monitor your counts. Report any signs of infection (fever, chills) immediately.
- Fatigue is a common side effect, but light exercise like walking can help improve energy levels and mood. Rest when needed, but aim to stay active as much as you can.
- Avoid large crowds and people who are sick to reduce the risk of infection. Wash your hands frequently and practice good hygiene to keep your immune system protected.
Fact Box
Chemical Class
Camptothecins
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Topoisomerase Inhibitor
Patient concerns
FAQs
What is Onivyde 43mg Infusion used for?
Onivyde 43mg Infusion is a chemotherapy drug used to treat metastatic pancreatic cancer, particularly in patients whose cancer has continued to progress after other treatments. It is used in combination with other chemotherapy drugs.
How is Onivyde 43mg Infusion administered?
Onivyde 43mg Infusion is given as an intravenous (IV) infusion, typically every two weeks, depending on your treatment plan. It is administered by a doctor or a nurse in a hospital or clinic setting.
What should I do if I experience severe side effects?
If you experience severe diarrhea, persistent vomiting, intense abdominal pain, or symptoms of infection (such as fever), contact your doctor immediately. These could be signs of serious complications that need prompt attention.
Can I take ONIVYDE if I am pregnant or breastfeeding?
No, ONIVYDE can harm an unborn baby, so you should avoid becoming pregnant while receiving this treatment. Additionally, you should not breastfeed while on ONIVYDE, as it could pass through breast milk and harm the baby.
Are there any foods or activities I should avoid while on Onivyde 43mg Infusion?
There are no specific foods to avoid, but it is important to stay hydrated and eat a balanced diet. It is also important to avoid live vaccines (such as those for chickenpox or measles) and to stay away from people who are sick, as Onivyde 43mg Infusion can lower your immune system.
Can I receive other medications or treatments while on treatment with Onivyde 43mg Infusion?
Let your doctor know about all other medications, supplements, and treatments you are using, as some may interact with Onivyde 43mg Infusion. Always consult your doctor before starting any new medication during your treatment.
How can I reduce the risk of infections during treatment?
Since Onivyde 43mg Infusion can lower your white blood cell count, it is important to practice good hygiene, avoid close contact with sick individuals, and report any signs of infection (fever, chills, cough) to your doctor right away.
How long will I need to be on Onivyde 43mg Infusion?
The duration of your treatment depends on how well your cancer responds to Onivyde 43mg Infusion and your overall health. Your doctor will regularly monitor your progress and adjust the treatment plan as needed.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Irinotecan liposome injection [Prescribing Information]. Cambridge, MA: Merrimack Pharmaceuticals, Inc.; 2015. [Accessed 30 Sep. 2024] (online) Available from:
- Pegylated liposomal [Summary of Product Characteristics]. Suresnes, France: Les Laboratoires Servier; 2021. [Accessed 30 Sep. 2024] (online) Available from:
- ONIVYDE (Irinotecan Liposome) [product Information]. [Accessed 30 Sep. 2024] (online) Available from:
- Irinotecan Liposome for Injection [Product Monograph]. Mississauga, ON: 2023. [Accessed 30 Sep. 2024] (online) Available from:
Marketer details
Name: Servier India Private Limited
Address: 1703, 17th Floor, Parinee Crescenzo, 'B' Wing, Plot No. 38 & 39 G Block behind MCA, MKC Bandra East, Mumbai 40051
Country of origin: India
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₹97862
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MRP₹99000 1% OFF
10.0 ml in 1 vial
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