Sazine DS 1000mg Tablet
Prescription Required
Product introduction
Sazine DS 1000mg Tablet is a medicine used to treat various inflammatory conditions, including rheumatoid arthritis and psoriatic arthritis (joints), ulcerative colitis, and Crohn’s disease (bowel). It reduces swelling and inflammation by blocking certain chemicals in the body.
Sazine DS 1000mg Tablet may be taken with or without food. Take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Drinking plenty of water while taking it can help prevent kidney issues, including kidney stones.
Common side effects of Sazine DS 1000mg Tablet include nausea, headache, vomiting, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do not resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To ensure Sazine DS 1000mg Tablet is safe for you, let your doctor know if you have any heart, kidney, or liver problems. Additionally, inform your doctor about all other medications you are currently taking. Your doctor may recommend regular blood tests to check your kidney and liver functions and blood components. Pregnant and breastfeeding mothers should seek medical advice before using this medicine.
Uses of Sazine Tablet
- Treatment of Rheumatoid arthritis
- Treatment of Psoriatic arthritis
- Treatment of Ulcerative colitis
- Treatment of Crohn’s disease
Benefits of Sazine Tablet
In Treatment of Rheumatoid arthritis
In individuals with rheumatoid arthritis, Sazine DS 1000mg Tablet helps slow joint damage and reduce pain and swelling. It also helps improve mobility and makes daily activities easier by decreasing joint inflammation.
In Treatment of Psoriatic arthritis
In psoriatic arthritis, Sazine DS 1000mg Tablet helps reduce joint pain, stiffness, and swelling. It also helps protect the joints from long-term damage and may also improve skin symptoms associated with psoriasis.
In Treatment of Ulcerative colitis
In individuals with ulcerative colitis, Sazine DS 1000mg Tablet helps control inflammation in the colon, reducing symptoms like diarrhea, rectal bleeding, and stomach cramps. It can also help maintain long-term remission and improve overall digestive comfort.
In Treatment of Crohn’s disease
Crohn's disease is a chronic inflammatory bowel disease (IBD) that affects the digestive tract. Sazine DS 1000mg Tablet helps reduce inflammation in the digestive tract, which can relieve symptoms of Crohn’s disease like diarrhea, stomach pain, and fatigue. Controlling inflammation also helps prevent flare-ups and improve overall gut health.
Side effects of Sazine Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sazine
- Gastrointestinal discomfort
- Headache
- Nausea
- Oligospermia (low sperm count)
- Vomiting
How to use Sazine Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazine DS 1000mg Tablet is to be taken with food.
How Sazine Tablet works
Sazine DS 1000mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocking the chemical messengers that cause inflammation (swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Sazine DS 1000mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Sazine DS 1000mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Sazine DS 1000mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Sazine DS 1000mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Sazine DS 1000mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazine DS 1000mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Liver
UNSAFE
Sazine DS 1000mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Sazine Tablet?
If you miss a dose of Sazine DS 1000mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Sazine DS 1000mg Tablet may take 6-8 weeks to show effects. Continue taking it as prescribed.
- Drink plenty of fluids while taking Sazine DS 1000mg Tablet to help prevent kidney issues, including kidney stones.
- Do not take Sazine DS 1000mg Tablet if you have an allergy to sulfa drugs or aspirin.
- Sazine DS 1000mg Tablet may cause your skin, urine, saliva, and tears to appear orange or yellow in color. This is normal and not harmful.
- Regular blood tests are necessary while taking this medicine to monitor liver function, kidney function, and blood component levels.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Aminosalicylic Acids Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
Interaction with drugs
Taking Sazine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Your doctor may monitor your blood cell count and adjust the doses as per the observations.
Concurrent use may increase the risk of low blood cell counts.
Patient concerns
FAQs
What is Sazine DS 1000mg Tablet, and what is it used for?
Sazine DS 1000mg Tablet belongs to a group of medicines called anti-inflammatory agents. It is used to treat various inflammatory conditions such as Crohn’s disease, rheumatoid arthritis, ulcerative colitis, and psoriatic arthritis.
Is Sazine DS 1000mg Tablet a steroid or a painkiller?
Sazine DS 1000mg Tablet is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease, in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).
I have been prescribed Sazine DS 1000mg Tablet for rheumatoid arthritis. When can I expect the pain in my joints to be better?
Sazine DS 1000mg Tablet does not work right away. It takes about 6 to 12 weeks to deliver the full effect. You may start feeling better in 4 weeks after starting Sazine DS 1000mg Tablet, but it can vary from person to person, and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.
For how long do I need to take Sazine DS 1000mg Tablet?
If you can tolerate Sazine DS 1000mg Tablet, which means the side effects do not bother you, then you have to continue Sazine DS 1000mg Tablet till the disease remains in remission. It is better to take Sazine DS 1000mg Tablet for the prescribed period.
Does the use of Sazine DS 1000mg Tablet for the treatment of arthritis affect kidney function?
Though it is uncommon, Sazine DS 1000mg Tablet may affect your kidney function. Therefore, your kidney function must remain normal before you start taking Sazine DS 1000mg Tablet. If your kidney functions become abnormal during the treatment, consult your doctor.
Do I need to get any blood tests done while on Sazine DS 1000mg Tablet therapy?
Your doctor will advise blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver, known as enzymes (liver function tests), and urine for protein and blood before you start treatment and at regular intervals.
Can Sazine DS 1000mg Tablet affect my fertility?
Decreased sperm count and infertility have been reported in some males. These may disappear once the Sazine DS 1000mg Tablet is discontinued.
Can I take azathioprine along with Sazine DS 1000mg Tablet?
You should avoid using Sazine DS 1000mg Tablet with azathioprine since there are chances of a decrease in blood cell count, which can be a serious side effect.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 632-33.
- Sulfasalazine [EMC Label]. Sandwich, Kent: Pfizer Limited; 2010 [revised Feb. 2014]. [Accessed 23 Jan. 2019] (online) Available from:
- Sulfasalazine [Patient Information Leaflet]. Uppsala, Sweden: Recipharm, Uppsala; 2018. [Accessed 18 Jun. 2019] (online) Available from:
- Sulfasalazine [Prescribing Information]. New York, New York: Pharmacia & Upjohn Co.; 2014. [Accessed 18 Jun. 2019] (online) Available from:
- Choi J, Fenando A. Sulfasalazine. [Updated 2022 Nov 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 06 Aug. 2023]. (online) Available from:
- National Health Service. Sulfasalazine. [Accessed 06 Aug. 2023]. (online) Available from:
- Sulfasalazine [Drug Information Booklet]. [Accessed 06 Aug. 2023]. (online) Available from
Marketer details
Name: Kasdap Healthcare Pvt Ltd
Address: 518, 5th Floor, Amamnora Chembers, Hadapsar, Pune, Maharashtra 411028
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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Question 1
What are you using this medicine for?
Rheumatoid arthritis
Psoriatic arthritis
Ulcerative colitis
Crohn’s disease
Others