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Chlorambucil

Information about Chlorambucil

Chlorambucil Uses

Chlorambucil is used in the treatment of malignant melanoma, Hodgkin’s disease, multiple myeloma, brain tumor, blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer and lung cancer.

How Chlorambucil works

Chlorambucil is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Common side effects of Chlorambucil

Bone marrow suppression

CONTENT DETAILS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Varun Gupta

MD Pharmacology, MBBS

Written By

Dr. Radhika Dua

MDS, BDS

Reviewed By

Dr. Shilpa Garcha

MD (Pharmacology), MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Lalit Kanodia

MBA, MD Pharmacology

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Varun Gupta

MD Pharmacology, MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Ashish Ranjan

MD (Pharmacology), MBBS

Written By

Dr. Radhika Dua

MDS, BDS

Reviewed By

Dr. Shilpa Garcha

MD (Pharmacology), MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Ashish Ranjan

MD (Pharmacology), MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Lalit Kanodia

MBA, MD Pharmacology

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Ashish Ranjan

MD (Pharmacology), MBBS

Written By

Dr. Radhika Dua

MDS, BDS

Reviewed By

Dr. Shilpa Garcha

MD (Pharmacology), MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Lalit Kanodia

MBA, MD Pharmacology

Last updated

28 Mar 2025 | 05:43 AM (UTC)

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Available Medicine for Chlorambucil

CelkeranCelon Laboratories Ltd

₹23241 variant(s)

ClokeranNatco Pharma Ltd

₹960 to ₹21902 variant(s)

ChloramaxGLS Pharma Ltd.

₹23701 variant(s)

Expert advice for Chlorambucil

Chlorambucil should be taken one hour before a meal or two hours after a meal.

Frequently asked questions for Chlorambucil

Chlorambucil

Q. How is Chlorambucil administered?

Chlorambucil is administered orally in tablet form.

Q. Why is Chlorambucil toxic to cancer cells/ how does Chlorambucil work?

Chlorambucil belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.

Q. Does Chlorambucil cause hair loss/constipation?

No, hair loss or constipation has not been reported with the use of Chlorambucil.

Q. What is Chlorambucil used for?

Chlorambucil is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).

Q. How is Chlorambucil excreted?

Chlorambucil is metabolized in liver to form nontoxic compounds which are excreted in urine.

Q. Does Chlorambucil need to be refrigerated?

Chlorambucil has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.