Chlorambucil

Chlorambucil is administered orally in tablet form.

Chlorambucil belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.

No, hair loss or constipation has not been reported with the use of Chlorambucil.

Chlorambucil is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).

Chlorambucil is metabolized in liver to form nontoxic compounds which are excreted in urine.

Chlorambucil has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.