Endomysial Antibody, IgG
Understanding Endomysial Antibody, IgG
What is Endomysial Antibody, IgG?
Endomysial Antibody, IgG test helps in the detection of IgG-endomysial antibodies for the diagnosis of dermatitis herpetiformis and celiac disease, and for monitoring adherence to a gluten-free diet. In celiac disease, the immune system mistakenly identifies gluten, a protein found in wheat, barley, and rye, as a foreign invader and produces IgG-EMA antibodies that attack the endomysium in the small intestine. This can lead to inflammation and damage to the intestinal lining, which can cause a range of symptoms including diarrhea, abdominal pain, skin rash, joint pain, and malabsorption of nutrients causing weight loss and fatigue. The detection of IgG-EMA in serum is commonly used as a diagnostic tool for celiac disease, In patients with low levels of IgA and children less than 3 years of age.
What is Endomysial Antibody, IgG used for?
- To diagnose Celiac disease when symptoms of Celiac Disease appear which includes abdominal pain, chronic irregular bowel movements, flatulence, blood in the stool, anemia, fatigue, joint pain, weight loss, etc.
- To diagnose Coeliac Disease in IgA deficient individuals, as an alternative to EMA-IgA
- To assess the efficacy of gluten-free diet in patients diagnosed with Celiac Disease who are on such a diet
- To screen people with blood relatives already diagnosed with Celiac disease
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