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Endomysial Antibody, IgG

Also referred as
Endomysial Antibody IgG Test
+3
EMA IgG Test
IgG-EMA Test
Celiac Disease Test
For men & women
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1 test
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₹2949
₹4899
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The Endomysial Antibody, IgG test is a blood test that detects IgG antibodies against endomysium, a connective tissue surrounding muscle fibers. This test supports the diagnosis of celiac disease and dermatitis herpetiformis, especially in people who have low levels of endomysial IgA antibodies or in young children.

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Understanding Endomysial Antibody, IgG

Endomysial antibodies (EMA) are special proteins produced by the immune system when it reacts abnormally to gluten, a protein found in wheat, rye, and barley. In people with celiac disease, gluten consumption triggers the body to make IgG endomysial antibodies (IgG-EMA) that target the endomysium, a thin layer of connective tissue around muscle fibers. This immune attack causes inflammation and damage in the small intestine, leading to poor absorption of nutrients.

People with celiac disease may experience symptoms such as diarrhea, bloating, stomach pain, weight loss, fatigue, anemia, skin rashes (dermatitis herpetiformis), or joint pain. IgG endomysial antibodies are detected in approximately 70%–80% of individuals with celiac disease or dermatitis herpetiformis, Detection rates vary based on diet, age, and disease severity. They appear in nearly all patients with severe gluten-sensitive enteropathy who are not following a gluten-free diet.

Doctors usually recommend the Endomysial Antibody, IgG test in patients who have low EMA-IgA antibody levels or in young children under 3 years of age, where IgA-based testing may not be reliable. 

The test supports monitoring treatment, as antibody levels typically decrease once gluten is removed from the diet. However, IgG antibodies may persist, and the test should not be used alone to assess mucosal healing.

No special preparation is required for the  Endomysial Antibody, IgG test. However, continue eating a diet that includes gluten for a few weeks before the test, unless the doctor advises otherwise.Avoiding gluten may cause false-negative results. Also, inform the doctor about all the medications and supplements currently being taken, as these may affect the test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does Endomysial Antibody, IgG measure?

The Endomysial Antibody, IgG test checks for the presence and levels of IgG endomysial antibodies in the blood. These antibodies are produced when the immune system reacts abnormally to gluten. High levels of these antibodies are associated with celiac disease, dermatitis herpetiformis, or gluten-related intestinal damage. If test results show elevated antibodies, doctors may recommend additional confirmatory tests, such as a tTG IgG test or an intestinal biopsy, to assess the extent of intestinal damage and make a clear diagnosis. On the other hand, low antibody levels usually indicate that the body is responding well to a gluten-free diet, making this test useful for diagnosis and monitoring treatment progress.

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Endomysial Antibody, IgG test price for other cities

Price inMumbaiRs. 2809
Price inAligarhRs. 4399
Price inCuttackRs. 4399
Price inAmritsarRs. 4399
Price inAsansolRs. 4399
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FAQs related to Endomysial Antibody, IgG

The Endomysial Antibody, IgG test supports the evaluation of IgG endomysial antibodies in the blood. It helps diagnose celiac disease and dermatitis herpetiformis, especially in patients who have low IgA antibody levels or in young children. It can also be used to monitor adherence to a gluten-free diet.
No, fasting is not required.
Yes. For accurate results, you must be on a diet that includes gluten for a few weeks before the test (unless your doctor advises otherwise). Avoiding gluten before the test may cause false-negative results.
The test is very safe. You may experience slight pain, bruising, or swelling at the site where the needle is inserted, but these effects are temporary and usually resolve quickly.
Doctors may recommend the test if you have symptoms like chronic diarrhea, bloating, stomach pain, unexplained weight loss, fatigue, anemia, or in children with growth problems. It may also be advised if you have malnutrition or a skin rash called dermatitis herpetiformis.
Both tests detect antibodies against endomysium. The IgA test is the primary and most specific test for celiac disease. The IgG test is usually done in patients who have IgA deficiency or in children under 3 years old, where IgA-based testing may not be reliable.
Yes. This test is particularly useful in children under 3 years of age, where IgA antibody levels may not have developed enough for reliable IgA testing.
Celiac disease is an autoimmune condition where the body reacts abnormally to gluten (a protein found in wheat, barley, and rye). Eating gluten triggers the immune system to attack the small intestine, causing damage, poor absorption of nutrients, and symptoms like diarrhea, bloating, abdominal pain, fatigue, weight loss, or anemia.
Gluten sensitivity (non-celiac gluten sensitivity) refers to people who develop symptoms like bloating, diarrhea, or fatigue after eating gluten but test negative for celiac disease. The Endomysial Antibody, IgG test does not diagnose gluten sensitivity, as this condition is identified by symptom relief on a gluten-free diet after excluding celiac disease and wheat allergy. It is milder than celiac disease but can still cause significant discomfort.
Dermatitis herpetiformis is a skin rash linked to celiac disease. It causes clusters of itchy, blister-like bumps, often on the elbows, knees, back, or buttocks. Around 70%–80% of patients with dermatitis herpetiformis test positive for IgG endomysial antibodies.
A positive test strongly suggests celiac disease or dermatitis herpetiformis. Your doctor may recommend further tests, such as tTG IgG or an intestinal biopsy for confirmation.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
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