Gamma Glutamyl Transferase

Also known as Gamma-glutamyl transpeptidase

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You need to provide

Blood

This test is for

Male, Female

Test Preparation

No special preparation is required.

Understanding Gamma Glutamyl Transferase

What is Gamma Glutamyl Transferase?

The Gamma Glutamyl Transferase test measures the amount of Gamma Glutamyl Transferase (GGT), a liver enzyme, in the body. This test is used to check for any blockage in the bile ducts and monitor the treatment response of liver diseases such as jaundice and hepatitis.

GGT is an enzyme that speeds up various chemical reactions in the body. It is abundantly found in the liver and in smaller quantities in many other body organs. The primary role of GGT is to transport molecules around the body. It also helps the liver metabolize medicines and other harmful substances (toxins) and aids in their elimination.

The GGT test is commonly used to detect liver diseases such as hepatitis, cirrhosis, or fatty liver disease. Your doctor may suggest this test when you show symptoms such as loss of appetite, belly pain and swelling, dark-colored urine, bruises, vomiting, and yellowing of the skin and eyes. It can also help identify alcohol-related liver problems, as GGT levels tend to rise with alcohol consumption. Usually, no special preparation is required for a GGT test. You may eat and drink as per your daily routine.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The test results will help them get insights into liver health, identify potential liver or bile duct issues, and formulate an overall treatment plan.

What is Gamma Glutamyl Transferase used for?

The Gamma Glutamyl Transferase test is done:

As part of a liver function test.
To monitor an existing liver disease and its treatment response.
To detect diseases associated with bile duct obstruction.
When alkaline phosphatase (ALP) enzyme levels are elevated.
To figure out if liver damage is due to a liver disease or bone disorder.
To monitor alcohol use disorder.

What does Gamma Glutamyl Transferase measure?

Gamma-Glutamyl Transferase (GGT) is an enzyme found in various organs, with the highest concentration in the liver. Usually, this enzyme is present in low levels in the blood. However, when there is liver damage or disease, GGT is released into the bloodstream, causing an increase in GGT levels. In addition to the liver, GGT can also be elevated in conditions affecting the bile ducts or the pancreas. It is usually, the first liver enzyme to rise in the blood when there is any damage or obstruction in the bile duct, making it one of the most sensitive liver enzyme tests for detecting bile duct problems.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Gamma Glutamyl Transferase

Frequently Asked Questions about Gamma Glutamyl Transferase

Q. Why do I need the Gamma Glutamyl Transferase test?

You might need the Gamma Glutamyl Transferase test if you show symptoms of liver disease or bile duct disorders, such as the yellowing of the skin or eyes, dark and pale urine, light-colored stool, nausea, vomiting, or belly pain.

Q. Is fasting required before the GGT test?

No, fasting is not required before the GGT test. You can eat or drink as per your normal routine before the test.

Q. Is there any risk associated with the GGT test?

There is usually no risk associated with this test. However, some people may feel a slight sting when a needle is pricked and may experience some bleeding that is normal and usually not bothersome. Rarely, some people may also experience slight swelling or bruising at the site of the needle prick. Applying ice 3-4 times a day for about a week may help reduce swelling and bruising. If it does not get better, consult your doctor.

Q. What happens if my GGT level is high?

If your GGT test result shows high levels of GGT enzyme, it might be a sign of obstructive liver disease, acute and chronic viral hepatitis, cirrhosis, fatty liver disease, cholestasis, alcoholic liver disease, and liver tumor. Consult your doctor to get the best possible advice.

Q. What are the natural ways to manage GGT levels?

You must consult your doctor to manage your GGT levels. However, some dietary interventions and healthy lifestyle choices can help you to keep your GGT levels in a healthy range. Eat liver-friendly fruits and vegetables, such as beetroots, grapes, cranberries, and watermelon. Also, avoid too much salty food, and limit your alcohol consumption.

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