Hepatitis A Virus, IgM
Understanding Hepatitis A Virus, IgM
What is Hepatitis A Virus, IgM?
The Hepatitis A Virus, IgM is a qualitative assay that detects Immunoglobulin M (IgM) antibodies produced by the immune system in response to the recent (acute) Hepatitis A virus (HAV) infection. It helps diagnose Hepatitis A and assess whether an individual has immunity to this disease.
Hepatitis A is a highly contagious, viral infection caused by the Hepatitis A virus (HAV). This infection is characterized by inflammation and other problems like enlargement of the liver and associated symptoms such as abdominal pain, loss of appetite, fatigue, nausea, vomiting, jaundice etc.
The Hepatitis A Virus, IgM test helps diagnose acute Hepatitis A, especially in individuals showing up with these symptoms or who have been exposed to someone with the HAV. Early diagnosis helps prevent the spread of the virus to others and guide appropriate medical care.
Upon exposure to HAV, IgM antibodies are produced at first to combat the virus. These antibodies are usually detectable from two weeks after symptoms onset to around six months later.The presence of these antibodies in the blood indicates a recent or current infection.
Doctors often recommend the Hepatitis A Virus, IgM test based on an individual’s medical history, symptoms, risk factors and physical examination findings.
No special preparation is required for this test. However, it's advisable to refrain from consuming alcohol before the test, as alcohol can impact liver function and potentially affect the test results. Also, inform the doctor about all the medications or supplements that you are taking, as well as history of recent vaccinations, as all these factors can influence the test results.
Lab test results may vary across laboratories. Abnormal test results require an expert interpretation, therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results and appropriate follow-up care, which may include additional testing to monitor liver function and ensure recovery.
What is Hepatitis A Virus, IgM used for?
The Hepatitis A Virus, IgM test is done:
- To detect acute or recent infection with the Hepatitis A virus (HAV).
- When there are symptoms such as abdominal pain, fatigue, jaundice etc., suggestive of a liver disease.
- To confirm the presence of antibodies indicating an active or recent HAV infection.
- To differentiate HAV from other types of hepatitis and liver diseases.
- To help identify individuals who need to be isolated to prevent the spread of the HAV.
- To monitor the spread of HAV within a community or outbreak settings.
What does Hepatitis A Virus, IgM measure?
The Hepatitis A Virus, IgM test is a qualitative assay that measures the presence of Immunoglobulin M (IgM) antibodies in the blood. These antibodies are produced by the immune system in response to an acute infection with the Hepatitis A virus (HAV). IgM antibodies are generated by the immune system within a few weeks of exposure. The presence of these antibodies indicates a recent or current infection, as IgM are the first antibodies that are produced in response to the HAV.
The Hepatitis A Virus, IgM test helps diagnose an acute Hepatitis A infection, especially in individuals exhibiting symptoms such as abdominal pain, loss of appetite, jaundice etc. Detecting IgM antibodies helps doctors confirm the diagnosis, differentiate it from other types of hepatitis ,and tailor appropriate treatment plans.
Interpreting Hepatitis A Virus, IgM results
Interpretations
- A positive test for Hepatitis A IgM usually indicates recent infection with Hepatitis A virus. The higher the level of antibodies, the stronger the infection with the virus.
- A negative test means absence of recent infection with Hepatitis A Virus. It does not mean that the person never had an infection with the virus.