Apaluside Tablet
Prescription Required
Product introduction
Apaluside Tablet is a medication used in the treatment of prostate cancer. It works by blocking the effects of testosterone on prostate cancer cells, which help slow down the growth and spread of prostate cancer. It is often used in combination with other therapies to treat prostate cancer.
Apaluside Tablet may be taken with or without food. However, always take it in the dose and duration prescribed by your doctor. Also, continue taking this medicine for as long as your doctor prescribes it, as missing a dose or stopping the treatment prematurely can reduce its effectiveness and may impact overall treatment outcomes.
Some common side effects of this medicine include fatigue, skin rash, hypertension, hot flush, arthralgia, diarrhea, falls, and weight loss. These side effects mostly occur at the initial stage of the treatment and usually disappear within a few days with continued treatment. However, let your doctor know if any of these side effects get worse or bother you. The doctor may also monitor you regularly to check the effectiveness of the medicine.
Apaluside Tablet is not suitable for everyone. To make sure it is safe for you, let your doctor know if you have a known history of allergic reactions to any of the ingredients of this medicine or have any other pre-existing medical conditions. Also, inform the doctor if you are taking, have recently taken, or might take any other medicines. This medicine is also contraindicated in pregnant or breastfeeding women, as it can cause harm to the developing fetus or nursing baby.
Apaluside Tablet may be taken with or without food. However, always take it in the dose and duration prescribed by your doctor. Also, continue taking this medicine for as long as your doctor prescribes it, as missing a dose or stopping the treatment prematurely can reduce its effectiveness and may impact overall treatment outcomes.
Some common side effects of this medicine include fatigue, skin rash, hypertension, hot flush, arthralgia, diarrhea, falls, and weight loss. These side effects mostly occur at the initial stage of the treatment and usually disappear within a few days with continued treatment. However, let your doctor know if any of these side effects get worse or bother you. The doctor may also monitor you regularly to check the effectiveness of the medicine.
Apaluside Tablet is not suitable for everyone. To make sure it is safe for you, let your doctor know if you have a known history of allergic reactions to any of the ingredients of this medicine or have any other pre-existing medical conditions. Also, inform the doctor if you are taking, have recently taken, or might take any other medicines. This medicine is also contraindicated in pregnant or breastfeeding women, as it can cause harm to the developing fetus or nursing baby.
Uses of Apaluside Tablet
Benefits of Apaluside Tablet
In Treatment of Cancer
Apaluside Tablet blocks the effects of testosterone on cancer cells, which in turn slows down the growth and spread of the cancer. It helps to control the cancer progression and improves the patient's overall condition and quality of life.
Side effects of Apaluside Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Apaluside
- Fatigue
- Skin rash
- High blood pressure
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Joint pain
- Diarrhea
- Fall
- Weight loss
How to use Apaluside Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apaluside Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Apaluside Tablet works
Prostate cancer cells depend on androgens to grow and survive. Even in cases where the cancer becomes resistant to standard hormonal therapies (castration-resistant), androgen receptors in the cancer cells continue to be active and promote cancer growth. Apaluside Tablet targets these androgen receptors, blocks their activation, and prevents them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Apaluside Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Apaluside Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Apaluside Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Apaluside Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Apaluside Tablet is safe to use in patients with kidney disease. No dose adjustment of Apaluside Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Apaluside Tablet is safe to use in patients with liver disease. No dose adjustment of Apaluside Tablet is recommended.
What if you forget to take Apaluside Tablet?
If you miss a dose of Apaluside Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Apaluside Tablet
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Quick tips
- If you have ever experienced a seizure, you must inform your doctor.
- If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
- Inform your doctor if you have a history of cardiovascular problems.
- Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
- Attend all follow-up visits with your doctor as scheduled.
- The doctor may monitor your liver function while you are on Apaluside Tablet treatment, as it can affect liver enzymes.
- If you have ever experienced a seizure, you must inform your doctor!
- If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
- Inform your doctor if you have a history of cardiovascular problems.
- Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
- Attend all follow-up visits with your doctor as scheduled.
- The doctor may monitor your liver function while you are on Apaluside Tablet treatment, as it can affect liver enzymes.
Fact Box
Chemical Class
Phenylimidazolidines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Androgen Receptor Antagonists
Interaction with drugs
Taking Apaluside with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Osimertinib with Apalutamide.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Sevoflurane with Apalutamide.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Hydroxychloroquine with Apalutamide.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Lenvatinib with Apalutamide.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Sevoflurane with Apalutamide.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Apalutamide [Summary of Product Characteristics]. Latina, Italy: Janssen Cilag SpA; 2019. [Accessed 27 Jul. 2023]. (online) Available from:
- Central Drugs Standard Control Organisation. List of new drugs approved in the year 2022 till date. [Accessed 27 Jul. 2023]. (online) Available from:
- National Cancer Institute. Apalutamide. [Accessed 27 Jul. 2023]. (online) Available from:
Country of origin: India
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