Hepatitis A Virus, IgG
Understanding Hepatitis A Virus, IgG
What is Hepatitis A Virus, IgG?
The Hepatitis A Virus, IgG test detects Immunoglobulin G (IgG) antibodies against past Hepatitis A virus (HAV) infection or vaccination. It helps determine long-term immunity to Hepatitis A virus and assess whether an individual has been previously exposed to or protected against the disease.
Hepatitis A is a highly contagious, viral infection caused by the Hepatitis A virus (HAV). This infection is characterized by inflammation of the liver and other problems like enlargement of the liver and associated symptoms such as abdominal pain, loss of appetite, fatigue, nausea, vomiting, jaundice etc.
The Hepatitis A Virus, IgG test is used to identify the presence of IgG antibodies in the blood, which indicates that a person has been previously infected with HAV or has been vaccinated against it. These antibodies usually develop several weeks to months after infection or vaccination and remain in the bloodstream for years, often for life.
Doctors typically recommend the Hepatitis A Virus, IgG test when evaluating an individual’s immunity status, especially if there’s a history of symptoms suggestive of Hepatitis A or if there’s a need to confirm past infection. This test is especially valuable for assessing whether you have developed immunity against Hepatitis A after vaccination. It also helps evaluate your risk of contracting Hepatitis A, which is crucial for high-risk groups such as healthcare workers or travelers traveling to areas where the virus is prevalent. This test helps in understanding an individual’s long-term protection against the virus and can guide further preventive measures or medical interventions.
No special preparation is required for this test. Inform the doctor about all the medications or supplements that you are taking, as well as history of recent vaccinations, as all these factors can influence the test results.
Lab test results may vary across laboratories. Abnormal test results require an expert interpretation, therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results and appropriate follow-up care, which may include additional testing to monitor liver function and ensure recovery.
What is Hepatitis A Virus, IgG used for?
The Hepatitis A Virus, IgG test is done:
- To confirm past exposure to the Hepatitis A virus (HAV) or immunity due to vaccination.
- To evaluate your risk of developing hepatitis A infection, especially in high-risk populations such as healthcare workers or travel history to areas where the virus is prevalent.
- To differentiate between a recent infection and past immunity.
- To determine the need for further vaccination or booster doses.
- To evaluate immunity status in individuals who have had symptoms suggestive of Hepatitis A in the past.
- In individuals who are scheduled to receive the hepatitis A vaccine and need to confirm their immune status.
What does Hepatitis A Virus, IgG measure?
The Hepatitis A Virus, IgG test is a qualitative assay that measures the presence of Immunoglobulin G (IgG) antibodies in the blood. These antibodies are produced by the immune system in response to a past Hepatitis A virus (HAV) infection or vaccination.IgG antibodies typically develop during the later stages of an infection and persist for a longer period, indicating long-term immunity. Their long-lasting presence in the blood helps confirm enduring protection and immunity against Hepatitis A.
The Hepatitis A Virus, IgG test helps confirm whether an individual has been previously exposed to HAV or has been successfully vaccinated. This information is crucial for understanding an individual’s immunity status and making informed decisions about further preventive measures or vaccinations.
Interpreting Hepatitis A Virus, IgG results
Interpretations
- Positive HAV IgG with negative IgM usually indicate no active infection but previous exposure to hepatitis A virus or recent vaccination
- Negative HAV IgG usually signifies no current or previous HAV infection
- If the total antibody test or hepatitis A IgG result is positive and someone has never been vaccinated against HAV, then the person has had past exposure to the virus. About 30% of adults over age 40 have antibodies to hepatitis A