Anti Soluble Liver Antigen

Anti-Soluble liver antigen (SLA) is a type of antibody found in patients suffering from hepatitis, an auto-immune disease. It is an ELISA-based in vitro test system for the qualitative determination of IgG antibodies against SLA in human serum. The anti-soluble liver antigen is detected in roughly one-third of the patients suffering from type 1 auto-immune hepatitis (AIH) but not in those suffering from type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The anti-SLA test is done by a simple blood sample test and then sent for diagnosis.

The reference range of anti-SLA negative is 0.0-20.0 U, Equivocal 20.1-24.9 U and positive is >25.0 U. What is Anti Soluble Liver Antigen used for? 1.To detect Autoimmune hepatitis (AIH). 2. Also to help diagnose patients with AIH relapse, after steroid therapies.